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馬輝——清華大學深圳研究生院教授

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馬輝，現任清華大學深圳研究生院生命與健康學部教授、博士生導師。

教育及工作經歷：

1982年吉林大學物理系，獲學士學位。

1982－1983年長春光機所光學專業，獲碩士學位。

1988年倫敦大學帝國理工學院物理系博士，專業方向為激光光譜、原子分子物理。

1988－1989英國倫敦大學帝國理工學院激光聯合體博士后。

1989－1991年大連化學物理研究所分子光譜實驗室博士后。

1991以后加入清華大學物理系原子分子納米科學教育部重點實驗室，任講師、1993年晉升副教授、2001年晉升教授、博士生導師。

2003年4月加入清華大學深圳研究生院創建“光學檢測與成像實驗室”。

2003.3.20-2014.1.20清華大學深圳研究院副院長。

2014.1.20至今，清華大學深圳研究院生命與健康學部主任。

學術兼職：

1、中國生物物理學會現代生物物理技術與方法專業委員會主任。

2、中國光學學會生物醫學光子學專業委員會副主任。

3、中國生物醫學工程學會數字醫療與醫學信息化分會常委。

4、中國電子學會生命電子學分會常委。

5、中國光學學會激光醫學專業委員會常務委員。

6、激光生物學雜志常務編委。

7、生物物理學報編委。

研究領域：

生物光子學（2006年之前）：包括：共焦與雙光子熒光成像、光學二次諧波成像、熒光各向異性度成像、熒光漲落譜，上述方法在生命科學研究中的應用。

生物醫學光學（現在）：基于光散射的無損成像方法及其應用研究，包括：

光學相干斷層成像

偏振光散射理論、方法和應用，包括：偏振光散射理論、模型與模擬方法，偏振特征表征與提取方法，偏振敏感測量與成像方法，偏振光散射的應用。

研究方向：

1991－1997年以前從事專業方向為激光光譜技術和原子分子物理，1998年以后從事生物物理實驗方法研究，研究方向為顯微成像與微區熒光分析。2004年赴清華大學深圳研究生院創建“光學檢測與成像實驗室”，展開多項研究內容，包括：生物組織中偏振散射與傳播行為研究、偏振光成像方法與應用研究、非線性光學顯微成像方法與應用研究。

偏振光散射與應用研究：

偏振是光的基本特征之一，但也是多年來一直被忽視的一個特征。我們周邊無處不在的光或多或少都有一些偏振成分，所有的物體都會改變光的偏振。偏振光的狀態采用四分量斯托克斯（Stokes）向量描述，其中一個分量是光強。探測光的偏振態，可以用一個4x4穆勒（Mueller）矩陣描述所有物體的偏振光學性質。由于人眼對偏振不敏感，我們只能看到周邊世界光強變化，即穆勒矩陣16個陣元中的一個。因此，偏振光測量包含更加豐富的信息。并且偏振信息對亞波長微觀結構更加敏感。研究、發展偏振光散射測量方法，可以大大豐富我們對周邊世界的感知能力。

研究方向

偏振光散射——理論、方法、技術、裝置、應用

研究內容

偏振光散射理論與計算模擬：利用各種單次散射理論，研究不同散射模型下偏振光在復雜介質中散射傳播過程，特別是偏振指標與微觀結構的對應關系。研究內容包括：單次散射理論與方法，散射模型，散射仿體，CPU與GPU模擬方法。

偏振光測量：研究不同偏振量測量方法和誤差傳遞規律，包括：分時與同時穆勒矩陣測量方法與技術，偏振測量誤差傳遞，對特異性結構敏感偏振量的測量方法。

偏振信息提取與特異性指標：獲得特異性微觀結構對應的偏振指標，包括：穆勒矩陣分解與變換，偏振態顯示，大數據關聯與統計分析。

偏振光散射應用：研究偏振散射方法在固體微觀結構（生物組織、材料）、氣體顆粒物和海洋微生物測量中的應用。

科研成果：

發表文章SCI收錄40余篇，發明專利5項，美國專利一項。

發表英文論文：

2015年

1. Ye Wang, Honghui He, Jintao Chang, Nan Zeng, Shaoxiong Liu, Migao Li, and Hui Ma*. “Differentiating characteristic microstructural features of cancerous tissues using Mueller matrix microscope”, Micron, 79:8-15, 2015.

2. Jintao Chang, Honghui He, Chao He, Yong Wang, Nan Zeng, Ran Liao, and Hui Ma*. “Optimization of GRIN lens Stokes polarimeter”, Applied Optics, 54(24):7424-7432, 2015.

3. Chao He, Honghui He, Jintao Chang, Yang Dong, Shaoxiong Liu, Nan Zeng, Yonghong He, and Hui Ma*. “Characterizing microstructures of cancerous tissues using multispectral transformed Mueller matrix polarization parameters”, Biomedical Optics Express, 6(8):2934-2945, 2015.

4. Yunfei Wang, Yihong Guo, Nan Zeng, Dongsheng Chen, Honghui He, and Hui Ma*. “Study on the validity of 3×3 Mueller matrix decomposition”, Journal of Biomedical Optics, 20(6):065003, 2015.

5. Chao He, Jintao Chang, Yong Wang, Ran Liao, Honghui He, Nan Zeng, and Hui Ma*. “Linear polarization optimized Stokes polarimeter based on four-quadrant detector”, Applied Optics, 54(14):4458-4463, 2015.

6. Ran Liao, and Hui Ma*. “Study on errors of nonsimultaneous polarized-light scattering measurements of suspended rod-shaped particles”, Applied Optics, 54(3):418-424, 2015.

7. Honghui He, Nan Zeng, Ran Liao, and Hui Ma*. “Progresses of polarization imaging techniques and their applications in cancer detections”, Progress in Biochemistry and Biophysics, 52(5):419-433, 2015.

8. Ran Liao, Honghui He, Nan Zeng, and Hui Ma*. “Characterizing the micro structure and kinetics of fast changing samples by simultaneous polarization measurements”, Proceedings of SPIE, 9322:93220C, 2015.

9. Yixi Liu, Le Liu, Yonghong He*, Liang Zhu, and Hui Ma，Decoding of Quantum Dots Encoded Microbeads Using a Hyperspectral Fluorescence Imaging Method, Analytical Chemistry, 87 (10): 5286–5293, 2015

10. Pengfei Zhang, Le Liu, Yonghong He *, Yanfei Zhou, Yanhong Ji, Hui Ma, Noninvasive and Real-Time Plasmon Waveguide Resonance Thermometry, Sensors, 15: 8481 -8498, 2015.

11. Pengfei Zhang, Le Liu, Yonghong He*, Zihao Xu, Yanhong Ji, Hui Ma, One-dimensional angular surface plasmon resonance imaging based array thermometer, Sensors & Actuators: B., 207: 254–261( 2015).

12. Yong Fan, Yu Ding, Hui Ma, Norio Teramae, Shuqing Sun*, YonghongHe， Optical waveguide sensor based on silicana notube arrays for label-free biosensing，Biosensors and Bioelectronics，67(2015)230–236

13. Huan Liu, Guohua Li, Xiangyu Sun, Yonghong He, Shuqing Sun*, Hui Ma，Microfluidic Generation of Uniform Quantum Dot-encoded Microbeads by Gelation of Alginate，RSC Adv., 2015, 5, 62706

2014年

14. Minghao Sun, Honghui He, Nan Zeng, E Du, Yihong Guo, Shaoxiong Liu, Jian Wu, Yonghong He, and Hui Ma*. “Characterizing the microstructures of biological tissues using Mueller matrix and transformed polarization parameters”, Biomedical Optics Express, 5(12):4223-4234, 2014.

15. Honghui He, Minghao Sun, Nan Zeng, E Du, Shaoxiong Liu, Yihong Guo, Jian Wu, Yonghong He, and Hui Ma*. “Mapping local orientation of aligned fibrous scatterers for cancerous tissues using backscattering Mueller matrix imaging”, Journal of Biomedical Optics, 19(10):106007, 2014.

16. E Du, Honghui He, Nan Zeng, Minghao Sun, Yihong Guo, Jian Wu, Shaoxiong Liu, and Hui Ma*. “Mueller matrix polarimetry for differentiating characteristic features of cancerous tissues”, Journal of Biomedical Optics, 19(7):076013, 2014.

17. Minghao Sun, Honghui He, Nan Zeng, E Du, Yonghong He, and Hui Ma*. “Reducing the orientation influence of Mueller matrix measurements for anisotropic scattering media”, Proceedings of SPIE, 9230:92300O, 2014 (Best student paper - oral).

18. Jintao Chang, Nan Zeng, Honghui He, and Hui Ma*. “Removing the polarization artifacts in Mueller matrix images recorded with a GRIN lens: a simulation approach”, Proceedings of SPIE, 9230:923008, 2014.

19. Ran Liao, and Hui Ma*, “Probing the suspended marine algae using polarized-light scattering”, 131129-040, OCEANS’14 MTS/IEEE Taipei, April 2014.

20. Jintao Chang, Nan Zeng, Honghui He, Yihong Guo, and Hui Ma, “Removing the polarization artifacts in mueller matrix images recorded with a birefringent gradient-index lens,” J. Biomed. Opt. 19(9), 095001 (2014).

21. Yihong Guo, Celong Liu, Nan Zeng, Honghui He, E Du, Yonghong He, and Hui Ma*. “Study on retardance due to well-ordered birefringent cylinders in anisotropic scattering media”, Journal of Biomedical Optics, 19(6):065001, 2014.

22. Jintao Chang, Nan Zeng, Honghui He, Yonghong He, and Hui Ma*. “Single-shot spatially modulated Stokes polarimeter based on a GRIN lens”, Optics Letters, 39(9):2656-2659, 2014.

23. Minghao Sun, Honghui He, Nan Zeng, E Du, Yihong Guo, Cheng Peng, Yonghong He, and Hui Ma*. “Probing microstructural information of anisotropic scattering media using rotation independent polarization parameters”, Applied Optics, 53(14):2949-2955, 2014.

24. Dongzhi Li, Honghui He, Nan Zeng, Weidong Xie, Ran Liao, Jian Wu, Yonghong He, and Hui Ma*. “Influence of absorption in linear polarization imaging of melanoma tissues”, Journal of Innovative Optical Health Sciences, 7(3):1450009, 2014.

25. E Du, Honghui He, Nan Zeng, Celong Liu, Yihong Guo, Ran Liao, Minghao Sun, Yonghong He, and Hui Ma*. “Characteristic features of Mueller matrix patterns for polarization scattering model of biological tissues”, Journal of Innovative Optical Health Sciences, 7(1):1350028, 2014.

26. Honghui He, Minghao Sun, Nan Zeng, E Du, Yihong Guo, Yonghong He, and Hui Ma*. “Mapping local anisotropy axis for scattering media using backscattering Mueller matrix imaging”, Proceedings of SPIE, 8952:89521B, 2014.

27. E Du, Honghui He, Nan Zeng, Yihong Guo, Minghao Sun, and Hui Ma*. “Mueller polarimetry for the detection of cancers”, Proceedings of SPIE, 8935:89350S, 2014.

28. Yihong Guo, Nan Zeng, Honghui He, Celong Liu, E Du, Yonghong He, and Hui Ma*. “Mueller matrix decomposition study on anisotropic medium including cylindrical scatterers and birefringent effect”, Proceedings of SPIE, 8952:89521C, 2014.

29. Yanfei Zhou, Pengfei Zhang, Yonghong He*, Zihao Xu, Le Liu, Yanhong Ji, Hui Ma, Plasmon waveguide resonance sensor using an Au–MgF2 structure, Applied Optics, 53(28) : 6344-6350, 2014.

30. Pengfei Zhang, Le Liu, Yonghong He*, Zhiyuan Shen, Jun Guo, Yanhong Ji, Hui Ma, Non-scan and real-time multichannel angular surface plasmon resonance imaging method, Applied Optics, 53 (26): 6037-6042, 2014.

31. Chan Du, Le Liu, Jun Guo, Yonghong He*, Jihua Guo, Shuqing Sun, Hui Ma, A biosensor using coupled plasmon waveguide resonance combined with hyperspectral fluorescence analysis, JIOHS, 7(1):1450017-1(2014).

32. Yong Fan, Yu Ding, Yafei Zhang, Hui Ma, Yonghong He and Shuqing Sun*，A SiO2-coated nanoporous alumina membrane for stable label-free waveguide biosensing，RSC Adv., 2014, 4, 62987–62995

33. Yong Fan, Kazuhiro Hotta, Akira Yamaguchi, Yu Ding, Yonghong He, Norio Teramae, Shuqing Sun, and Hui Ma, "Highly sensitive real-time detection of DNA hybridization by using nanoporous waveguide fluorescence pectroscopy," APPLIED PHYSICS LETTERS 105, 031103 (2014).

2013年

34. Yihong Guo, Nan Zeng, Honghui He, Tianliang Yun, E Du, Ran Liao, Yonghong He, and Hui Ma*. “A study on forward scattering Mueller matrix decomposition in anisotropic medium”, Optics Express, 21(15):18361-18370, 2013.

35. Honghui He, Nan Zeng, E Du, Yihong Guo, Dongzhi Li, Ran Liao, Yonghong He, and Hui Ma*. “Two-dimensional and surface backscattering Mueller matrices of anisotropic sphere-cylinder scattering media: a quantitative study of influence from fibrous scatterers”, Journal of Biomedical Optics, 18(4):046002, 2013.

36. Dongzhi Li, Honghui He, Nan Zeng, E Du, Ran Liao, Yonghong He, Hui Ma*, Shaoxiong Liu, and Minghua Li. “Polarization imaging and scattering model of cancerous liver tissues”, Journal of Innovative Optical Health Sciences, 6(3):1350025, 2013.

37. E Du, Honghui He, Nan Zeng, Celong Liu, Yihong Guo, Ran Liao, Minghao Sun, Yonghong He, and Hui Ma*. “Characteristic features of Mueller matrix patterns for polarization scattering model of biological tissues”, Journal of Innovative Optical Health Sciences, 6(4):1350028, 2013.

38. Honghui He, Nan Zeng, Tianliang Yun, Yonghong He, and Hui Ma*. “Linear polarization reflectance of anisotropic scattering medium”, Optik, 124(17):2619-2622, 2013.

39. Honghui He, Nan Zeng, E Du, Yihong Guo, Dongzhi Li, Ran Liao, and Hui Ma*. “A possible quantitative Mueller matrix transformation technique for anisotropic scattering media”, Photonics & Lasers in Medicine, 2(2):129-137, 2013.

40. Heng Shi, Zhiyi Liu, Xiaoxiao Wang, Jun Guo, Le Liu, Lin Luo, Jihua Guo, Hui Ma, Shuqing Sun and Yonghong He. "A symmetrical optical waveguide based surface plasmon resonance biosensing system.", Sensors and Actuators B: Chemical,2013,Vol.185,91-96

41. Honghui He, Nan Zeng, E Du, Yihong Guo, Dongzhi Li, Ran Liao and Hui Ma. "A possible quantitative Mueller matrix transformation technique for anisotropic scattering media."， Photonics and Lasers in Medicine,2013,2(2): 129-137

42. Feng Li, Jing Wang, Yuming Lai, Chong Wu, Shuqing Sun, Yonghong He, Hui Ma, "Ultrasensitive and selective detection of copper (II) and mercury (II) ions by dye-coded silver nanoparticle-based SERS probes", Biosensors and Bioelectronics, Volume 39, Issue 1, 15 January 2013, Pages 82–87

43. Fei Peng, Jing Wang, Guanglu Ge, Tao He, Lixin Cao, Yonghong He, Hui Ma and Shuqing Sun. "Photochemical reduction of CO2 catalyzed by silicon nanocrystals produced by high energy ball milling.", Materials Letters,2013,Vol.92,65-67

2012年

44. E Du, Honghui He, Nan Zeng, Yihong Guo, Ran Liao, Yonghong He, and Hui Ma*. “Two-dimensional backscattering Mueller matrix of sphere–cylinder birefringence media”, Journal of Biomedical Optics, 17(12):126016, 2012.

45. Honghui He, Nan Zeng, Dongzhi Li, Ran Liao, and Hui Ma*. “Quantitative Mueller matrix polarimetry techniques for biological tissues”, Journal of Innovative Optical Health Sciences, 5(3):1250017, 2012.

46. Honghui He, Nan Zeng, Tianliang Yun, Yonghong He, Hui Ma. "Linear polarization reflectance of anisotropic scattering medium", Optik -International Journal for Light and Electron Optics,2012,124(17),2619–2622

47. Zhiyi Liu, Le Liu, Xiaoxiao Wang, Heng Shi, Xinyuan Chong, Suihua Ma, Yanhong Ji, Jihua Guo, Hui Ma and Yonghong He. "Polarization-interferometry-based wavelength-interrogation surface plasmon resonance imager for analysis of microarrays.", Journal of Biomedical Optics,2012,17(3),036002

48. Jing Wang, Yuexian Liu, Fei Peng, Chunying Chen, Yonghong He, Hui Ma, Lixin Cao, Shuqing Sun, "A General Route to Efficient Functionalization of Silicon Quantum Dots for High-performance Fluorescent Probes", Small, Volume 8, Issue 15, pages 2430–2435, August 6, 2012

49. Chong Wu1, Yongsheng Wang, Xuemingyue Han, Xinming Hu, Qianyi Cheng, Baohang Han, Qian Liu, Tianling Ren, Yonghong He, Shuqing Sun and Hui Ma, "Site-selective assembly of quantum dots on patterned self-assembled monolayers fabricated by laser direct-writing", Nanotechnology 23 235302 doi:10.1088/0957-4484/23/23/235302

2011年

50. Ran Liao, Nan Zeng, Dongzhi Li, Tianliang Yun, Yonghong He, and Hui Ma*. “Penetration depth of linear polarization imaging for two-layer anisotropic samples”, Applied Optics, 50(23):4681-4687, 2011.

51. Dongzhi Li, Ran Liao, Tianliang Yun, Yonghong He and Hui Ma*. “Polarization scattering imaging of cancerous tissue”, Chinese Journal of Lasers, 38(S1):104002, 2011.

52. Yong Zhou,Nan Zeng,Yanhong Ji,Yao Li,Xiangsong Dai,Peng Li,Lian Duan,Hui Ma and Yonghong He. "Iris as a reflector for differential absorption low-coherence interferometry to measure glucose level in the anterior chamber", Journal of Biomedical Optics,2011,Vol.16(1),015004

53. Yong Zhou, Ye Hu, Nan Zeng, Yanhong Ji, Xiangsong Dai, Peng Li, Hui Ma, and Yonghong He. "Noninvasive monitoring of Pirenoxine Sodium concentration in aqueous humor based on dual-wavelength iris imaging technique.", Biomedical optics express,2011,2(2):231

54. Zhiyi Liu, Heng Shi, Le Liu, Sunan Deng, Yanhong Ji, Suihua Ma, Hui Ma and Yonghong He. "Line-Monitoring, Hyperspectral Fluorescence Setup for Simultaneous Multi-Analyte Biosensing.", Sensors,2011,11(11): 10038-10047

55. Bolin Hu, Nan Zeng, Zhiyi Liu, Yanhong Ji, Weidong Xie, Qing Peng, Yong Zhou, Yonghong He and Hui Ma. "Two-dimensional singlet oxygen imaging with its near-infrared luminescence during photosensitization.", Journal of Biomedical Optics,2011,16(1), 016003-016003-7

56. Zhiyuan Shen, Min Wang, Yanhong Ji, Yonghong He, Xiangsong Dai, Peng Li, and Hui Ma. "Transverse flow velocity quantification using optical coherence tomography with correlation.", Laser physics letters,2011,8(4):318-323

2010年

57. Dongzhi Li, Ran Liao, Nan Zeng, Yonghong He and Hui Ma*. “Comparison of two linear differential polarization imaging methods in tissue characterization”, Proceedings of SPIE, 7845 78452L, 2010.

58. Tianliang Yun, Nan Zeng, Honghui He, Wei Li, Ran Liao, Yonghong He and Hui Ma*. “A sphere-cylinder scattering model for skeletal muscle”, Proceedings of SPIE, 7845 78452N, 2010.

59. Nan Zeng, Honghui He, Tinaliang Yun and Hui Ma*. “Study on the backscattering Mueller matrix of the sphere-cylinder scattering model of anisotropic tissues”, Proceedings of SPIE, 7845 78450M, 2010.

60. Honghui He, Nan Zeng, Wei Li, Tianliang Yun, Ran Liao, Yonghong He, and Hui Ma*. “Two-dimensional backscattering Mueller matrix of sphere-cylinder scattering medium”, Optics Letters, 35(14):2323-2325, 2010.

61. Honghui He, Nan Zeng, Ran Liao, Tianliang Yun, Wei Li, Yonghong He, and Hui Ma*. “Application of sphere-cylinder scattering model to skeletal muscle”, Optics Express, 18(14):15104-15112, 2010.

62. Ran Liao, Nan Zeng, Xiaoyu Jiang, Dongzhi Li, Tianliang Yun, Yonghong He, and Hui Ma*. “Rotating linear polarization imaging for quantitative characterization of anisotropic tissues”, Journal of Biomedical Optics, 15(3), 2010.

63. Ran Liao, Nan Zeng, Dongzhi Li, Tianliang Yun, Yonghong He, and Hui Ma*. “A study on penetration depth of polarization imaging”, Journal of Innovative Optical Health Sciences, 3(3):177-181, 2010.

64. Zhiyi Liu, Suihua Ma, Yanhong Ji, Le Liu, Zhaoxu Hu, Jihua Guo, Hui Ma and Yonghong He. "Quasi-confocal, multichannel parallel scan hyperspectral fluorescence imaging method optimized for analysis of multicolor microarrays.", Analytical chemistry,2010,82(18):7752-7757

65. Zhiyi Liu, Yonghong He, Le Liu, Suihua Ma, Xinyuan Chong, Zhaoxu Hu, Hui Ma and Jihua Guo. "Two-channel, quasi-confocal parallel scan fluorescence imaging for detection of biochips.", Optics and Lasers in Engineering,2010,48(9),849-855

2009年

66. Tianliang Yun, Nan Zeng, Wei Li, Dongzhi Li, Xiaoyu Jiang, and Hui Ma*. “Monte Carlo simulation of polarized photon scattering in anisotropic media”, Optics Express, 17(19):16590-16602, 2009.

67. Nan Zeng, Xiaoyu Jiang, Qiang Gao, Yonghong He, and Hui Ma*. “Linear polarization difference imaging and its potential applications”, Applied Optics, 48(35):6734-6739, 2009.

68. Tianliang Yun, Wei Li, Xiaoyu Jiang, and Hui Ma*. “Monte Carlo simulation of polarized light scattering in tissues”, Journal of Innovative Optical Health Sciences, 2(2):131-135, 2009.

69. Wei Li, Nan Zeng, Yonghong He and Hui Ma*. “Propagation of polarized light in anisotropic medium”, Proceedings of SPIE, 7175 71751C, 2009.

70. Dongzhi Li, Ran Liao, Nan Zeng, Yonghong He and Hui Ma*. “Measurement of degree of orientation of high polymer using rotating linear polarization imaging”, Proceedings of SPIE, 7519 75190U, 2009.

2008年

71. Nan Zeng, Yonghong He and Hui Ma. "Application of optical coherence tomography in nacre identification and characterization.", Microwave and optical technology letters,2008,50(2):442-445

72. Le Liu, Yonghong He, Ying Zhang, Suihua Ma, Hui Ma, and Jihua Guo. "Parallel scan spectral surface plasmon resonance imaging.", Applied optics,2008,47(30):5616-5621

2007年

73. Xiaoyu Jiang, Nan Zeng, Yonghong He, and Hui Ma*. “Investigation of linear polarization difference imaging based on rotation of incident and backscattered polarization angles”, Progress in Biochemistry and Biophysics, 34(6):659-663, 2007.

74. Wei Li, Yi Wang, Hanrong Shao, Yonghong He, and Hui Ma*. “Probing rotation dynamics of biomolecules using polarization based fluorescence microscopy”, Microscopy Research and Technique, 70(4):390-395, 2007.

75. Jun Xu*, Jin Bao, Baohua Guo, Hui Ma*, Tianliang Yun, Liang Gao, Guoqiang Chen, and Tadahisa Iwata. “Imaging of nonlinear optical response in biopolyesters via seco7nd harmonic generation microscopy and its dependence on the crystalline structures”, Polymer, 48(1):348-355, 2007.

76. Yonghong Shao, Yonghong He, Hui Ma*, Nan Nan, Longsheng Qian, and Shuxia Wang. “Carotenoid levels measured by resonance raman in vivo”, Spectroscopy and Spectral Analysis, 27(11):2258-2261, 2007.

77. Wei Li, Hanrong Shao, Honghui He, Yonghong He, and Hui Ma*. “Polarization gated imaging in turbid media: a study with monte carlo simulation”, Proceedings of SPIE, 6534 65340A, 2007.

78. Nana Wang, Hanrong Shao, Yonghong He and Hui Ma*. “Contrast of the polarization difference projection images with linearly and circularly polarized lights”, Proceedings of SPIE, 6534 65340B, 2007.

2006年

79. Fanbo Meng, and Hui Ma*. “A comparison between photon counting histogram and fluorescence intensity distribution analysis”, Journal of Physical Chemistry B, 110(51):25716-25720, 2006.

80. Fanbo Meng, and Hui Ma*. “Extended photon counting histogram and fluorescence intensity distribution analysis approaches for optically biased photon counting statistics”, Journal of Physical Chemistry B, 110(19):9667-9673, 2006.

81. Hanrong Shao, Yonghong He, Wei Li, and Hui Ma*. “Polarization-degree imaging contrast in turbid media: a quantitative study”, Applied Optics, 45(18):4491-4496, 2006.

82. Wei Li, Yi Wang, Hanrong Shao, Yonghong He, and Hui Ma*. “Two-photon fluorescence anisotropy imaging”, Proceedings of SPIE, 6047 60472R, 2006.

83. Hanrong Shao, Yonghong He, Yonghong Shao, and Hui Ma*. “Contrast enhancement subsurface optical imaging with different incident polarization states”, Proceedings of SPIE, 6047 60470Z, 2006.

2005年

84. Fanbo Meng, and Hui Ma*. “Fluorescence correlation spectroscopy analysis of diffusion in a laser gradient field: A numerical approach”, Journal of Physical Chemistry B, 109(12):5580-5585, 2005.

85. Fanbo Meng, Bo Chen, Guang Liu, Jianying Ding, and Hui Ma*. “Fluorescence fluctuation spectroscopy and its artifacts: simulations and tests”, Science in China Series G-Physics Mechanics & Astronomy, 48(3):336-344, 2005.

86. Xuefeng Wang, Yi Wang, Yan Jiang, and Hui Ma. “Two-photon fluorescence anisotropy imaging”, Progress in Biochemistry and Biophysics, 32(2):161-167, 2005.

2004年

87. Wang J, Ji L, Lin X S, Ma H. Tracking deforming aortas in two-photon autofluorescence images and its application on quantitative evaluation of aorta-related drugs. Computerized Medical Imaging and Graphics, 2004, 28(1-2):51-59.

88. Wang Y, Wang X F, Wang C, Ma H. Simultaneously multi-parameter determination of hematonosis cell apoptosis by two-photon and confocal laser scanning microscopy. Journal of Clinical Laboratory Analysis, 2004, 18(5):271-275.

89. Liu G, Chen B, Meng F B, Ma H, Chen D Y. Fluorescence fluctuation spectroscopy with strong background fluorescence - An Monte Carlo approach. Spectroscopy and Spectral Analysis, 2004, 24(11):1379-1383. (in Chinese)

90. Meng F B, Chen B, Liu G, Ma H. Diffusion in laser gradient field studied by fluorescence correlation spectroscopy. Chinese Physics Letters, 2004, 21(4):760-763.

91. Lin X S, Pan L, Hu J Y, Ma H, Chen D Y. Backward second harmonic generation Imaging of tissues. Progress in Biochemistry and Biophysics, 2004, 31(1):83-88. (in Chinese)

92. Ding J Y, Chen B, Meng F B, Ma H. Fluorescence correlation spectroscopy with saturated excitation. Acta Physica Sinica, 2004, 53(8):2503-2508. (in Chinese)

2003年

93. Deng Y, Lin X S, Zheng Z, Deng J G, Chen J C, Ma H, Chen G Q. Poly(hydroxybutyrate-co-hydroxyhexanoate) promoted production of extracellular matrix of articular cartilage chondrocytes in vitro. Biomaterials, 2003, 24(23):4273-4281.

94. Wang J, Ji L, Ma H. Reconstruction of deforming aortas in two-photon autofluorescence image sequences. Applied Optics, 2003, 42(5):834-844.

95. Zhao M, Jin L, Chen B, Ding Y, Ma H, Chen D Y. Afterpulsing and its correction in fluorescence correlation spectroscopy experiments. Applied Optics, 2003, 42(19):4031-4036.

2002年

96. Xu H, Zhang C Y, Ma H, Liu B, Chen D Y. Progress in multi-photon excitation and its applications. Progress in Chemistry, 2002, 14(2):81-86. (in Chinese)

97. Zhang C Y, An C C, Wang R Y, Gong Y X, Ma H, Chen D Y, Chen Z L. Capillary electrophoresis and circular dichroism study of trichosanthin and its mutants. Talanta, 2002, 57(3):467-473.

2001年

98. Chen B, Meng F B, Ma H, Ding Y, Jin L, Chen D Y. Monte Carlo simulation of FCS in a laser gradient field. Spectroscopy and Spectral Analysis, 2001, 21(3):263-266. (in Chinese)

99. Ci Y X, Zhai Q, Wang S, Chang W B, Zhang C Y, Ma H, Chen D Y, Zhao M Z, Hu S W. Voltammetric studies of the effect of Cisplatin-liposome on Hela cells. Talanta, 2001, 55(4):693-698.

100. Ding Y, Meng F B, Chen B, Ma H, Lei J, Chen D Y. An experimental study on the fluorescence correlation spectroscopy in laser gradient field. Acta Physica Sinica, 2001, 50(11):2269-2274. (in Chinese)

101. Meng F B, Chen B, Ding Y, Ma H, Jin L, Chen D Y. Fluorescence correlation spectroscopy in laser gradient field. Chinese Science Bulletin, 2001, 46(19):1589-1592.

102. Zhang C Y, Gong Y X, Ma H, An C C, Chen D Y. Reactive oxygen species involved in trichosanthin-induced apoptosis of human choriocarcinoma cells. Biochemical Journal, 2001, 355(653-661.

103. Zhang C Y, Gong Y X, Ma H, An C C, Chen D Y. Studying the effect of trichosanthin on choriocarcinoma cells with both two-photon and confocal laser scanning microscopy. Progress in Biochemistry and Biophysics, 2001, 28(5):717-721. (in Chinese)

104. Zhang C Y, Li Y P, Ma H, Li S W, Xue S B, Chen D Y. Effect of BCL-2 on Harringtonine-induced apoptosis and intracellular Ca2+ mobilization in human leukemia HL-60 cells. Research on Chemical Intermediates, 2001, 27(9):991-1000.

105. Zhang C Y, Li Y P, Ma H, Li S W, Xue S B, Chen D Y. Simultaneous multi-parameter observation of Harring-tonine-treating HL-60 cells with both two-photon and confocal laser scanning microscopy. Science in China Series C-Life Sciences, 2001, 44(4):383-391.

106. Zhang C Y, Ma H, Ding Y, Jin L, Chen D Y, Miao Q, Nie S M. Studies on quantum dots-labeled trichosanthin. Chemical Journal of Chinese Universities-Chinese, 2001, 22(1):34-37. (in Chinese)

107. Zhang C Y, Wei T T, Ma H, Ding Y, Chen D Y, Hou J W, Chen C, Xin W J. Reactive oxygen species are involved in nitric oxide-induced apoptosis of neurons. Progress in Biochemistry and Biophysics, 2001, 28(1):81-85. (in Chinese)

2000年

108. Zhang C Y, Ma H, Nie S M, Ding Y, Jin L, Chen D Y. Quantum dot-labeled trichosanthin. Analyst, 2000, 125(6):1029-1031.

109. Zhang C Y, Wei T T, Ma H, Chen C, Xin W J, Chen D Y. A photoelectric method for analyzing NO-Induced apoptosis in cultured neuronal cells. Electroanalysis, 2000, 12(17):1414-1418.

110. Wei T T, Zhang C Y, Hou J W, Chen C, Ma H, Chen D Y, Xin W J. Reactive oxygen species are involved in nitric oxide-induced apoptosis in rat cortical neurons. Research on Chemical Intermediates, 2000, 26(9):875-883.

發表期刊論文

1 基于四象限探測器的斯托克斯向量測量儀何超; 常金濤; 王勇; 廖然; 謝軍; 馬輝紅外與毫米波學報 2016/01

2 基于LS-DYNA模擬碰撞誘發的裂紋擴展馬輝; 曾勁; 吳志淵; 秦朝燁東北大學學報(自然科學版) 2015/11

3 海底觀測網中上位機與服務器通信協議的設計謝軍; 馬輝; 李秀計算機工程與科學 2015/09

4 偏振光成像技術用于腫瘤病變檢測的研究進展優先出版何宏輝; 曾楠; 廖然; 馬輝生物化學與生物物理進展 52(5):419-433, 2015.

5 補償波段建模方法及其在血清葡萄糖光譜分析中的應用優先出版謝軍; 馬輝; 潘濤分析試驗室 2015/03

6 基于穆勒矩陣的偏振顯微鏡及其在生物醫學領域的應用王曄; 何宏輝; 曾楠; 謝軍; 廖然; 常金濤; 孫明皓; 馬輝世界復合醫學 2015/01

7 基于光譜解調的對稱波導型表面等離子體共振傳感研究張怡龍; 劉樂; 郭峻; 張鵬飛; 郭繼華; 馬輝; 何永紅光譜學與光譜分析 2015/02

8 偏振光散射無標記活體“顯微”成像技術研究進展孫明皓; 何宏輝; 杜娥; 曾楠; 馬輝生命科學儀器 2014/Z1

9 深圳的產學研合作:歷史經驗與現狀思考曾國屏; 王路昊; 楊君游; 馬輝科學與管理 2013/06

10 海洋微生物偏振光散射的雙組分模型廖然; 馬輝海洋學報(中文版) 2011/06

11 模擬高放玻璃固化體在低氧地下水中的長期蝕變行為研究甘學英; 張振濤; 苑文儀; 王雷; 邢海青; 白楊; 馬輝輻射防護 2011/02

12 90-19/U玻璃體在地下水溶液中的蝕變速率研究甘學英; 張振濤; 苑文儀; 王雷; 邢海青; 白楊; 馬輝中國原子能科學研究院年報 2009/00

13 90-19/U玻璃固化體在蝕變速率下降階段的腐蝕機理研究甘學英; 張振濤; 苑文儀; 王雷; 邢海青; 白楊; 馬輝中國原子能科學研究院年報 2009/00

14 三維譜域光學相干層析成像系統的研制段煉; 何永紅; 朱銳; 馬輝; 郭繼華中國激光 2009，36(10):2528-2533

15 旋轉線偏振光成像方法在紡織品纖維檢測中的應用高強; 曾楠; 馬輝中國激光 2009,36(9):2380-2385

16 使用并行掃描光譜SPR成像方法檢測DNA微陣列劉樂; 何永紅; 馬輝; 郭繼華生物物理學報 2009/S1

17 旋轉線偏振光成像方法及其在皮膚上的應用初探李冬至; 廖然; 曾楠; 馬輝生物物理學報 2009/S1

18 各向異性生物組織中偏振光傳輸的模擬與實驗云天梁; 曾楠; 李偉; 馬輝光學學報 2009,29(7):1926-1929

19 李偉，曾楠，云天梁，馬輝. 各向異性散射介質對偏振光傳播的影響. 中國激光, 2009,36(s1):222

20 朱銳,何永紅,郭繼華,曾楠,馬輝. 頻域光學相干層析系統的快速色散補償算法研究. 光子學報,2008，37(Sup 2)

21 頻域偏振敏感光學相干層析系統的研制及應用研究代祥松; 曾楠; 何永紅; 馬輝光電子.激光，2008，19(11):1502-1506

22 用于玉石結構分析的光學相干層析技術曾楠; 何永紅; 馬輝光學精密工程 ,2008,16(7):1335

23 偏振干涉角度調制SPR傳感技術研究及應用進展張瑩; 曾楠; 馬綏華; 馬輝; 何永紅; 劉樂; 郭繼華生物技術通報 2008,(S1):481-485

24 偏振門用于對散射介質成像的蒙特卡羅模擬研究李偉; 何永紅; 馬輝光子學報 ,2008,37(3),518-522

25 眼底OCT成像系統的研制何衛紅; 何永紅; 李鵬; 朱毅; 邵永紅; 梁瑞生; 曾楠; 馬輝光學精密工程 ,2008,16(3):438-443

26 共振拉曼光譜在體測量類胡蘿卜素含量邵永紅; 何永紅; 馬輝; 南楠; 錢龍生; 王淑霞光譜學與光譜分析，2007，27(11):2258-2261

27 采用OCT系統對組織光學通透的研究孫惠霞; 李鵬; 何永紅; 馬輝激光生物學報 ,2007,16(5):521-526

28 偏振光在散射介質中的傳播與成像李偉; 云天梁; 何宏輝; 曾楠; 馬輝中國科學(G輯:物理學力學天文學) ,2007,37(B10):94-100

29 應用于珍珠檢測的光學相干層析技術曾楠; 何永紅; 馬輝; 王淑霞中國激光 2007，34(8):1140-1145

30 基于旋轉偏振角的線偏振掃描成像方法研究蔣嘯宇; 曾楠; 何永紅; 馬輝生物化學與生物物理進展，2007，34（6），659-663

31 光學相干層析用于牙齒病變的檢測王淑霞; 何永紅; 曾楠; 高應俊; 邵永紅; 馬輝激光生物學報 ,2007,16(3):355-358

32 基于醫用顯微鏡的光學相干層析系統設計邵永紅; 何永紅; 馬輝; 王淑震; 朱毅激光雜志 2007,2,017

33 光學相干層析圖像層狀結構的增強與定量測量朱毅; 何永紅; 李鵬; 何衛紅; 高應俊; 曾楠; 馬輝光學學報，2007，27(3): 515-520

34 一種無信息丟失的光學相干層析圖像校正方法朱毅; 何永紅; 李鵬; 高應俊; 邵永紅; 馬輝激光與紅外 ,2007,37(3):288-291

35 群相可控光學延遲線色散特性分析邵永紅; 何永紅; 王淑霞; 馬輝光學精密工程 2006,14(6)

36 光學相干層析成像技術用于裸鼠皮膚霉菌感染研究邵永紅; 何永紅; 馬輝; 王淑霞; 張雅歐激光生物學報 ,2006,15(5),536-539

37 檢測工程聚合物材料新方法研究邵永紅; 何永紅; 馬輝; 王淑霞激光與紅外 2006，36(9):878-885

38 鼠眼睛前段光學相干層析成像邵永紅; 何永紅; 馬輝; 王淑霞激光與紅外 , 2006, 36(8):694-695

39 從不定度量空間形式到不定度量空間形式的等距浸入(英文) 陳維桓; 李海中; 馬輝數學進展 2005/06

40 小檗堿對人高轉移肺癌系(PG)細胞增殖的影響及機制研究蔣艷; 王毅; 郝鈺; 汪雪峰; 邱全瑛; 黃啟福; 馬輝中國病理生理雜志 2005/11

41 用光學二次諧波成像技術觀察皮膚內不同種類的膠原王毅; 鮑進; 盛巡; 李萍; 馬輝激光生物學報 2005/04

42 基于終端發送速率與丟幀率的IEEE 802.11性能優化李賀武; 吳建平; 馬輝; 張培云; 羅世新清華大學學報(自然科學版) 2005/04

43 熒光漲落譜的Monte Carlo模擬與應用孟凡波; 陳波; 劉廣; 丁建英; 馬輝中國科學G輯:物理學、力學、天文學 2005,35(1),62-70

44 雙光子激發熒光各向異性度的成像汪雪峰; 王毅; 蔣艷; 馬輝生物化學與生物物理進展 ,2005,32(2),161-167

45 丁建英,陳波,孟凡波,馬輝. 飽和激發情況下的熒光關聯譜測量. 物理學報,2005,53(8),2503-2508

46 基于競爭終端個數區間的IEEE802.11性能優化李賀武; 吳建平; 馬輝; 張培云; 羅世新軟件學報 2004/12

47 強熒光背景環境中熒光漲落譜——蒙特卡羅模擬研究劉廣; 陳波; 孟凡波; 馬輝; 陳瓞延光譜學與光譜分析 2004/11

48 人參皂苷Rg1和Rh1對樹突狀細胞功能的影響(英文) 王毅; 郝鈺; 婁金麗; 馬輝; 邱全瑛中國病理生理雜志 2004/10

49 飽和激發情況下的熒光關聯譜測量丁建英; 陳波; 孟凡波; 馬輝物理學報 2004/08

50 內嵌流程定義語言的局放在線監測診斷系統涂卓; 高文勝; 談克雄; 馬輝高電壓技術 2004/06

51 生物活組織的背向二次諧波成像林幸筍; 潘琳; 胡金云; 馬輝; 陳瓞延生物化學與生物物理進展 2004/01

52 小檗堿對人肺癌細胞株與人臍靜脈內皮細胞粘附的影響蔣艷; 王毅; 郝鈺; 汪雪峰; 邱全瑛; 馬輝中國病理生理雜志 2003/11

53 關于李群間映射的伸縮度和拓撲度(英文) 徐峰; 賀慧霞; 馬輝中國科學技術大學學報 2003/05

54 Veronese映射剛性定理的另一證明(英文) 賀慧霞; 馬輝; 徐峰中國科學院研究生院學報 2003/03

55 三氧化二砷誘導人鱗狀細胞癌細胞凋亡的研究汪晨; 黎小珠; 桑建利; 汪雪峰; 馬輝臨床皮膚科雜志 2003/04

56 大規模無線局域網的設計與實現馬輝; 李賀武; 李星計算機工程與應用 2003/03

57 利用分子雷達研究嗎啡對PC12細胞的作用機制史琛; 于小麗; 陸久怡; 張春陽; 金雷; 馬輝; 張德昌; 陳瓞延分析科學學報 2002/05

58 多光子技術及其應用研究進展徐慧; 張春陽; 馬輝; 陳瓞延分析科學學報 2002/05

59 多光子技術及其應用研究進展徐慧; 馬輝; 劉昪; 陳瓞延化學進展 2002/02

60 一種新的紅細胞源降壓因子對大鼠血管的保護作用龐煥; 石磊; 馬寧; 王玉堂; 文允鎰; 孫非; 林幸筍; 馬輝科學通報 2002/04

61 R2,1中類時Weingarten曲面的B?cklund變換馬輝數學研究與評論 2002/01

62 共聚焦激光掃描顯微術研究天花粉蛋白對小鼠胚胎細胞的作用機制徐慧; 張春陽; 馬輝; 陳瓞延分析科學學報 2001/06

63 激光梯度場中熒光關聯譜學的實驗研究丁堯; 孟凡波; 陳波; 馬輝; 金雷; 陳瓞延物理學報 2001/11

64 雙光子及共聚焦激光掃描顯微術研究天花粉蛋白對人絨癌細胞的作用機制張春陽; 貢宜萱; 馬輝; 安成才; 陳瓞延生物化學與生物物理進展 2001/05

65 梯度場中熒光關聯譜測量的Monte Carlo模擬陳波; 孟凡波; 馬輝; 丁堯; 金雷; 陳瓞延光譜學與光譜分析 2001/03

66 雙光子及共聚焦激光掃描顯微鏡同時多參數觀察三尖杉酯堿誘導的HL-60細胞凋亡張春陽; 李艷平; 馬輝; 李素文; 薛紹白; 陳瓞延中國科學(C輯:生命科學) 2001/03

67 激光梯度場中熒光關聯譜孟凡波; 陳波; 丁堯; 馬輝; 金雷; 陳瓞延科學通報 2001/11

68 活性氧參與一氧化氮誘導的神經細胞凋亡張春陽; 衛濤濤; 馬輝; 丁堯; 陳瓞延; 侯京武; 陳暢; 忻文娟生物化學與生物物理進展 2001/01

69 量子點標記天花粉蛋白的研究張春陽; 馬輝; 丁堯; 金雷; 陳瓞延; 苗琦; 聶書明高等學校化學學報 2001/01

70 細胞內鈣離子的光學分析方法研究進展張春陽; 陳波; 馬輝; 陳瓞延分析科學學報 2000/06

71 綠色熒光蛋白在細胞分析中的應用張春陽; 馬輝; 陳瓞延分析科學學報 2000/05

72 花粉蛋白誘導胞內鈣離子信號波動的研究貢宜萱; 安成才; 殷征; 陳章; 張春陽; 馬輝生物技術通報 2000/05

73 腔衰蕩吸收多指數模型研究馬輝; 董國軒; 何秋榮; 朱方強; 姜開利; 陳瓞延光譜學與光譜分析 1998/02

74 腔衰蕩吸收測量中光源線寬影響研究朱方強; 姜開利; 何秋榮; 董國軒; 馬輝; 陳瓞延化學物理學報 1998/01

75 腔內回旋衰減——一種新的超高靈敏吸收光譜技術董國軒; 馬輝; 江開利; 何秋榮; 陳瓞延物理 1997/08

76 利用REMPI方法測量BaF高里德堡系列光譜馬輝; 李儉; 劉耀明; 陳瓞延化學物理學報 1995/04

77 提高DFWM光譜測量信噪比的研究馬輝; 張全法; 李儉; 薛猛; 陳瓞延化學物理學報 1995/03

會議論文：

1. Hui Ma. "Polarization imaging:techniques, applications and the physics insights.", Russian-Chinese Workshop on Biophotonics and Biomedical Optics:Book of Abstracts.2012:29

2. Dongsheng Chen, Nan Zeng, Celong Liu and Hui Ma. "Characterization of muscle stretching and damage using polarization-sensitive optical coherence tomography (PS-OCT)", Optics in Health Care and Biomedical Optics V,2012,December 11,Proc.SPIE,Vol.8553,85533C

3. Dongsheng Chen, Nan Zeng, Celong Liu and Hui Ma. "A method of simulating polarization-sensitive optical coherence tomography based on a polarization-sensitive Monte Carlo program and a sphere cylinder birefringence model.", Optics in Health Care and Biomedical Optics V,2012,December 11,Proc.SPIE,Vol.8553,855320

4. Tianliang Yun, Nan Zeng, Honghui He, Wei Li, Ran Liao, Yonghong He and Hui Ma. "A sphere-cylinder scattering model for skeletal muscle.", Optics in Health Care and Biomedical Optics IV,2010,November 08,Proc.SPIE,Vol.7845,78452N

5. Nan Zeng,Honghui He,Tianliang Yun and Hui Ma. "Study on the backscattering Mueller matrix of the sphere-cylinder scattering model of anisotropic tissues.", Optics in Health Care and Biomedical Optics IV,2010,November 08,Proc.SPIE,Vol.7845,78450M

6. Dongzhi Li, Ran Liao, Nan Zeng, Yonghong He and Ma Hui. "Comparison of two linear differential polarization imaging methods in tissue characterization.", Optics in Health Care and Biomedical Optics IV,2010,November 08,Proc.SPIE,Vol.7845,78452L

7. Wei Li, Nan Zeng, Yonghong He and Hui Ma. "Propagation of polarized light in anisotropic medium.", Optical Interactions with Tissue and Cells XX,2009,February 12,Proc.SPIE,Vol.7175,71751C

8. Le Liu, Suihua Ma, Yonghong He, Weiping Lu, Hui Ma, Yaou Zhang and Jihua Guo. "A new parallel scan spectral SPR 2D sensing system.", Plasmonics in Biology and Medicine VI,2009,February 18,Proc.SPIE,Vol.7192,719210

9. Dongzhi Li, Ran Liao, Nan Zeng, Yonghong He and Hui Ma. "Measurement of degree of orientation of high polymer using rotating linear polarization imaging.", Eighth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2009),2009,,Proc.SPIE,October 28,Vol.7519,75190U

10. Suihua Ma, Le Liu, Zhong Zhang, Yonghong He, Zhiyi Liu, Hui Ma, Jihua Guo and Zhanshan Wang. "Experimental study on the influence of the metal film thickness on surface plasmon resonance biosensors.", Plasmonics in Biology and Medicine VI,2009,February 17,Proc.SPIE 7192,719211

11. 劉樂，何永紅，馬輝，郭繼華. 使用并行掃描光譜SPR成像方法檢測DNA微陣列. 生物物理學報《新方法新技術》專題報告,2009,S1,175

12. 李冬至,廖然,曾楠,馬輝. 旋轉線偏振光成像方法及其在皮膚上的應用初探. 生物物理學報《新方法新技術》專題報告,2009,S1,497

13. Qiang Gao, Xiaoyu Jiang, Nan Zeng, Yonghong He and Hui Ma. "Linear Polarization Different Imaging and its Potential Applications.", Asia Optical Fiber Communication and Optoelectronic Exposition and Conference. Optical Society of America,2008,AOE 2008,Asia.IEEE,2008:1-3

14. Nan Zeng, Tianliang Yun, Wei Li and Hui Ma. "Monte Carlo simulation of polarized light scattering in anisotropic medium.",Asia Optical Fiber Communication and Optoelectronic Exposition and Conference. Optical Society of America,2008,AOE 2008,Asia.IEEE,2008:1-3

15. Wei Li, Hui Ma."Gatings for optical imaging in turbid media.", Russian-Chinese Workshop on Biophotonics & Biomedical Optics:Book of Abstracts,2007: 10

16. Wei Li, Hanrong Shao, Honghui He, Yonghong He and Hui Ma. "Polarization gated imaging in turbid media: a study with Monte Carlo simulation", Fifth International Conference on Photonics and Imaging in Biology and Medicine,2007,May 01,Proc.SPIE,Vol.6534,65340A

17. Wei Li, Yi Wang, Hanrong Shao, Yonghong He and Hui Ma. "Two-photon fluorescence anisotropy imaging", Fourth International Conference on Photonics and Imaging in Biology and Medicine,2006,October 27,Proc.SPIE,Vol.6047,60472R

18. Xiaoyu Jiang, Hui Ma. "Reflective Polarization Imaging for Characterizing Structural and Optical Properties of Tissues.", Russian-Chinese Workshop on Biophotonics & Biomedical Optics:Book of Abstracts,2007: 15

19. Nana Wang, Hanrong Shao, Yonghong He and Hui Ma. "Contrasts of the polarization difference projection images with linearly and circularly polarized lights.", Fifth International Conference on Photonics and Imaging in Biology and Medicine,2007,May 01,Proc.SPIE,Vol.6534,65340B

20. Xiaoyu Jiang, Wei Li, Tianliang Yun, Zeng Nan, Yonghong He and Hui Ma. "Rotating linear differential polarization imaging for quantitative characterization of superficial tissues.", Optical Fiber Communication and Optoelectronics Conference,Asia.IEEE,2007:584-586

21. Hanrong Shao, Yonghong He, Yonghong Shao and Hui Ma. "Contrast enhancement subsurface optical imaging with different incident polarization states.", Fourth International Conference on Photonics and Imaging in Biology and Medicine,2006,October 27,Proc.SPIE,Vol.6047,60470Z

22. Yi Zhu, Peng Li, Weihong He, Yingjun Gao, Yonghong He, Hui Ma. "Layer structures localization in optical coherence tomography images.", Biophotonics,Nanophotonics and Metamaterials,2006.Metamaterials 2006.International Symposium on.IEEE,2006:50-53

23. Peng Li, He, Yonghong, Hui Ma. "Spectral-Domain Optical Coherence Tomography and Applications for Biological Imaging.", Biophotonics, Nanophotonics and Metamaterials, 2006.Metamaterials 2006.International Symposium on.IEEE,2006:222-225

24 偏振光散射及其應用馬輝 “廣東省光學學會2013年學術交流大會”暨“粵港臺光學界產學研合作交流大會” 中國會議 2013-12-13

25 各向異性介質的穆勒矩陣分解偏振光學特征郭亦鴻; 曾楠; 何宏輝; 何永紅; 馬輝中國光學學會2011年學術大會中國會議 2011-09-05

26 骨骼肌組織球柱偏振光散射模型何宏輝; 曾楠; 云天梁; 何永紅; 馬輝中國光學學會2011年學術大會中國會議 2011-09-05

27 癌變組織偏振光散射成像李冬至; 廖然; 曾楠; 何永紅; 馬輝中國光學學會2011年學術大會中國會議 2011-09-05

28 微生物偏振光散射的雙組份模型廖然; 馬輝中國光學學會2011年學術大會中國會議 2011-09-05

29 各向同性組織癌變的偏振光散射模型李冬至; 廖然; 曾楠; 何永紅; 馬輝中國光學學會2011年學術大會中國會議 2011-09-05

30 各向異性介質Mueller矩陣的定量分析杜娥; 曾楠; 何宏輝; 何永紅; 馬輝中國光學學會2011年學術大會中國會議 2011-09-05

31 線偏振差成像方法及其應用李冬至; 廖然; 曾楠; 何永紅; 馬輝中國生物醫學工程學會成立30周年紀念大會暨2010中國生物醫學工程學會學術大會中國會議 2010-12-02

32 90-19/U玻璃體在地下水溶液中的蝕變速率研究甘學英; 張振濤; 苑文儀; 王雷; 邢海青; 白楊; 馬輝中國原子能科學研究院年報 2009 中國會議 2010-07-01

33 90-19/U玻璃固化體在蝕變速率下降階段的腐蝕機理研究甘學英; 張振濤; 苑文儀; 王雷; 邢海青; 白楊; 馬輝中國原子能科學研究院年報 2009 中國會議 2010-07-01

34 使用并行掃描光譜SPR成像方法檢測DNA微陣列劉樂; 何永紅; 馬輝; 郭繼華第十一次中國生物物理學術大會暨第九屆全國會員代表大會中國會議 2009-07-12

35 旋轉線偏振光成像方法及其在皮膚上的應用初探李冬至; 廖然; 曾楠; 馬輝第十一次中國生物物理學術大會暨第九屆全國會員代表大會中國會議 2009-07-12

36 熒光偏振成像及其應用馬輝中國光學學會2006年學術大會中國會議 2006-09

37 多模式光學顯微復合成像馬輝第十次中國生物物理學術大會中國會議 2006-05

38 光學相干層析成像術對組織光學特征的測量及其在組織通透過程的應用孫惠霞; 李鵬; 何永紅; 馬輝第十次中國生物物理學術大會中國會議 2006-05

39 混濁介質中偏振光散射的蒙卡模擬李偉; 何宏輝; 邵漢榮; 何永紅; 馬輝第十次中國生物物理學術大會中國會議 2006-05

40 Monte Carlo方法模擬偏振光在混濁介質中的散射李偉; 何宏輝; 邵漢榮; 馬輝第十次中國生物物理學術大會中國會議 2006-05

41 偏振光成像與應用研究邵漢榮; 王娜娜; 何永紅; 馬輝第十次中國生物物理學術大會中國會議 2006-05

42 聚羥基脂肪酸酯的二次諧波及其聚集態結構研究徐軍; 鮑進; 郭寶華; 馬輝 2005年全國高分子學術論文報告會中國會議 2005-10

43 二次諧波成像及其在生物醫學領域的應用馬輝中國光學學會2004年學術大會中國會議 2004

44 非線性顯微光學成像及其應用馬輝第九次全國生物物理大會學術會議中國會議 2002-05

45 三氧化二砷誘導人鱗狀上皮癌細胞凋亡汪晨; 汪雪峰; 史琛; 馬輝; 陳瓞延; 張春陽; 黎小珠; 桑建立 2002中國中西醫結合皮膚性病學術會議中國會議 2002-03

46 多光子激光掃描顯微技術研究天花粉蛋白對絨毛膜上皮癌細胞的作用機制張春陽; 馬輝; 陳瓞延第三屆全國現代生物物理技術學術討論會中國會議 2000-10

47 活性氧參與一氧化氮誘導的神經細胞凋亡張春陽; 衛濤濤; 馬輝; 丁堯; 陳瓞延; 侯京武; 陳暢; 忻文娟第五屆全國自由基生物學與自由基醫學學術討論會中國會議 2000-10

48 血管彈力纖維雙光子自熒光成像與分析林幸筍; 孫飛; 王玨; 馬輝; 趙靜波; 季梁; 陳瓞延第三屆全國現代生物物理技術學術討論會中國會議 2000-10

49 低能離子注入生物種子深度濃度分布的TPLSM研究周宏余; 陸挺; 朱光華; 汪新福; 王超; 丁曉紀; 陳曉波; 吳虎才; 宋海; 馬輝第十一屆全國核物理大會中國會議 2000-10

光學檢測與成像實驗室

實驗室簡介：

光學檢測與成像實驗室于2004年5月成立，2010被評選為深圳市重點實驗室。實驗室的科研隊伍由四名教授、一名副教授、兩名講師、一名實驗員和三十多名博士、碩士研究生組成。實驗室在研究生院支持下，現擁有實驗儀器設備固定資產超過800 萬，包括熒光顯微鏡、多種半導體光源(包括寬帶高功率SLD 和不同波長的多個全固化連續激光器)和超快激光光源、光電倍增管和制冷CCD等探測器、數字示波器，以及各類光學、光機械元器件和光學檢測所需的一些基本科研裝備。驗實室面積近300 平方米，擁有光學平臺9個、以及光學暗室、光電子學實驗室、光學鍍膜實驗室以及機械加工等輔助設施，各類微機三十多臺。

招生信息：

目前實驗室每年招收理學碩士研究生5-7名；生物醫學工程碩士研究生5-7名；理學博士研究生3-5名；除此之外，還招收清華大學-伯克利學院博士研究生2名，碩士生2-5名。

研究團隊成員：

馬輝教授、博士生導師

郭繼華教授、博士生導師

何永紅教授、博士生導師

孫樹清教授、博士生導師

曾楠副教授

廖然講師

何宏輝講師

郭峻工程師

研究方向：

實驗室主要開展應用于生命科學和醫學診斷中的光學檢測與成像方法研究。包括：

生物組織中的光子傳輸行為研究；

偏振光成像方法與應用；

表面等離子體共振傳感方法、技術與應用；

光學相干層析成像方法與技術；

生物醫用納米材料與納米探針；

納米結構及表面的修飾與傳感；

實驗室承擔的科研項目

目前實驗室承擔的在研項目二十余項，其中國家、省部級科研項目十九項，總經費兩千余萬元：

國家重大科研儀器研制項目: 模塊化穆勒矩陣顯微鏡及其典型臨床應用演示

國家重大科研儀器設備研制專項：手部生物特征的物理屬性和生化成份采集儀

國家自然科學基金項目: 癌變組織穆勒矩陣與現場診斷方法研究

國家自然科學基金項目: 偏振組織光學模型與偏振成像病理診斷方法研究

國家自然科學基金項目: 大氣顆粒物粒徑分群統計和源解析的偏振光學方法研究

國家自然科學基金項目: 偏振散射組織表征方法及其在惡性腫瘤診斷中的應用

國家自然科學基金項目: 與樣品取向無關的偏振光散射多波長成像方法及應用研究

國家自然科學基金項目：SPR超光譜熒光生物芯片檢測方法及其應用研究

國家自然科學基金項目：房水糖濃度檢測的雙波長弱相干干涉差分吸收方法研究

國家自然科學基金項目：多功能硅基納米材料的制備及其在生物醫學中的應用

國家自然科學基金項目：基于新型納米結構光波導熒光增強研究及其在超靈敏傳感中的應用

深圳市技術攻關項目：海洋浮游動物在線成像儀關鍵技術研發

深圳市科技計劃技術開發項目: 定量偏振光成像標準模塊及軟件系統

深圳技術開發項目：現場藻類熒光分類分析儀

深圳國際合作項目：細胞模型的OCT及SPR原位實時檢測研究

深圳市科技計劃基礎研究項目: 基于偏振光成像的海洋水下微型生物識別與監測技術研發

深圳市科技計劃基礎研究項目: 多模態智能化納米分子影像探針及其在疾病診斷與研究中的應用

深圳市科技計劃基礎研究項目: 醫用無毒硅納米晶體熒光探針的高效制備與應用研究

深圳市科技研發資金國際科技合作項目: 偏振內窺及臨床應用研究

主要成果

2004年實驗室成立以來已在國內外重要期刊上發表論文一百八十余篇，申請國家發明專利16項，美國專利1項。研制出適用于材料生產的在線監測、人工組織工程的在線監測、中醫形態學診斷等領域的光學檢測成像系統共6套，應用于臨床眼科診斷成像系統已經轉移到深圳市企業，產品已經推向市場。實驗室成員獲得2004年和2007年國家發明二等獎，2005年科學技術一等獎，2009年廣西科技進步二等獎一項。

成果論文：

2015

1. Ye Wang, Honghui He, Jintao Chang, Nan Zeng, Shaoxiong Liu, Migao Li, and Hui Ma*. “Differentiating characteristic microstructural features of cancerous tissues using Mueller matrix microscope”, Micron, 79:8-15, 2015.

2. Jintao Chang, Honghui He, Chao He, Yong Wang, Nan Zeng, Ran Liao, and Hui Ma*. “Optimization of GRIN lens Stokes polarimeter”, Applied Optics, 54(24):7424-7432, 2015.

3. Chao He, Honghui He, Jintao Chang, Yang Dong, Shaoxiong Liu, Nan Zeng, Yonghong He, and Hui Ma*. “Characterizing microstructures of cancerous tissues using multispectral transformed Mueller matrix polarization parameters”, Biomedical Optics Express, 6(8):2934-2945, 2015.

4. Yunfei Wang, Yihong Guo, Nan Zeng, Dongsheng Chen, Honghui He, and Hui Ma*. “Study on the validity of 3×3 Mueller matrix decomposition”, Journal of Biomedical Optics, 20(6):065003, 2015.

5. Chao He, Jintao Chang, Yong Wang, Ran Liao, Honghui He, Nan Zeng, and Hui Ma*. “Linear polarization optimized Stokes polarimeter based on four-quadrant detector”, Applied Optics, 54(14):4458-4463, 2015.

6. Ran Liao, and Hui Ma*. “Study on errors of nonsimultaneous polarized-light scattering measurements of suspended rod-shaped particles”, Applied Optics, 54(3):418-424, 2015.

7. Honghui He, Nan Zeng, Ran Liao, and Hui Ma*. “Progresses of polarization imaging techniques and their applications in cancer detections”, Progress in Biochemistry and Biophysics, 52(5):419-433, 2015.

8. 何宏輝, 曾楠, 廖然, 馬輝*. 偏振光成像技術用于腫瘤病變檢測的研究進展. 生物化學與生物物理進展, 52(5):419-433, 2015.

9. Ran Liao, Honghui He, Nan Zeng, and Hui Ma*. “Characterizing the micro structure and kinetics of fast changing samples by simultaneous polarization measurements”, Proceedings of SPIE, 9322:93220C, 2015.

10. Yixi Liu, Le Liu, Yonghong He*, Liang Zhu, and Hui Ma，Decoding of Quantum Dots Encoded Microbeads Using a Hyperspectral Fluorescence Imaging Method, Analytical Chemistry, 87 (10): 5286–5293, 2015

11. Pengfei Zhang, Le Liu, Yonghong He *, Yanfei Zhou, Yanhong Ji, Hui Ma, Noninvasive and Real-Time Plasmon Waveguide Resonance Thermometry, Sensors, 15: 8481 -8498, 2015.

12. Yilong Zhang, Le Liu, Yi Tao, Yonghong He* Pengfei Zhang, Zhonghua Cai, A fiber-based fluorometric system for algal classification in situ, Optics & Laser Technology, 2015

13. Pengfei Zhang, Le Liu, Yonghong He*, Zihao Xu, Yanhong Ji, Hui Ma, One-dimensional angular surface plasmon resonance imaging based array thermometer, Sensors & Actuators: B., 207: 254–261( 2015).

14. Yong Fan, Yu Ding, Hui Ma, Norio Teramae, Shuqing Sun*, YonghongHe， Optical waveguide sensor based on silicana notube arrays for label-free biosensing，Biosensors and Bioelectronics，67(2015)230–236

15. Xuemingyue Han, Xiangyu Sun, Tao He,* and Shuqing Sun*, Formation of Highly Stable Self-Assembled Alkyl Phosphonic Acid Monolayers for the Functionalization of Titanium Surfaces and Protein Patterning，Langmuir 2015, 31, 140−148

16. Huan Liu, Guohua Li, Xiangyu Sun, Yonghong He, Shuqing Sun*, Hui Ma，Microfluidic Generation of Uniform Quantum Dot-encoded Microbeads by Gelation of Alginate，RSC Adv., 2015, 5, 62706

17. Yuming Lai, Shuqing Sun, Tao He, Sebastian Schl¨ucker and Yuling Wang，Raman-encoded microbeads for spectral multiplexing with SERS detection，RSC Adv., 2015, 5, 13762

18. Feng Li , Jing Wang , Shuqing Sun , * Hai Wang , Zhiyong Tang , and Guangjun Nie *，Facile Synthesis of pH-sensitive Germanium Nanocrystals with High Quantum Yield for Intracellular Acidic Compartment Imaging， small 2015, 11, No. 16, 1954–1961

2014

1. Minghao Sun, Honghui He, Nan Zeng, E Du, Yihong Guo, Shaoxiong Liu, Jian Wu, Yonghong He, and Hui Ma*. “Characterizing the microstructures of biological tissues using Mueller matrix and transformed polarization parameters”, Biomedical Optics Express, 5(12):4223-4234, 2014.

2. Honghui He, Minghao Sun, Nan Zeng, E Du, Shaoxiong Liu, Yihong Guo, Jian Wu, Yonghong He, and Hui Ma*. “Mapping local orientation of aligned fibrous scatterers for cancerous tissues using backscattering Mueller matrix imaging”, Journal of Biomedical Optics, 19(10):106007, 2014.

3. E Du, Honghui He, Nan Zeng, Minghao Sun, Yihong Guo, Jian Wu, Shaoxiong Liu, and Hui Ma*. “Mueller matrix polarimetry for differentiating characteristic features of cancerous tissues”, Journal of Biomedical Optics, 19(7):076013, 2014.

4. Minghao Sun, Honghui He, Nan Zeng, E Du, Yonghong He, and Hui Ma*. “Reducing the orientation influence of Mueller matrix measurements for anisotropic scattering media”, Proceedings of SPIE, 9230:92300O, 2014 (Best student paper - oral).

5. Jintao Chang, Nan Zeng, Honghui He, and Hui Ma*. “Removing the polarization artifacts in Mueller matrix images recorded with a GRIN lens: a simulation approach”, Proceedings of SPIE, 9230:923008, 2014.

6. Ran Liao, and Hui Ma*, “Probing the suspended marine algae using polarized-light scattering”, 131129-040, OCEANS’14 MTS/IEEE Taipei, April 2014.

7. Yanfei Zhou, Pengfei Zhang, Yonghong He*, Zihao Xu, Le Liu, Yanhong Ji, Hui Ma, Plasmon waveguide resonance sensor using an Au–MgF2 structure, Applied Optics, 53(28) : 6344-6350, 2014.

8. Pengfei Zhang, Le Liu, Yonghong He*, Zhiyuan Shen, Jun Guo, Yanhong Ji, Hui Ma, Non-scan and real-time multichannel angular surface plasmon resonance imaging method, Applied Optics, 53 (26): 6037-6042, 2014.

9. Chuan Liu, Heng Shi, Yonghong He*, Multi-channel, line-monitoring sensing approach based on long-range surface plasmons, Plasmonics, 9(3): 513-518,2014.

10. Pengfei Zhang, Le Liu, Yi Tao, Qiang Huang, Heng Shi, Chan Du, Xihui Zhang, Yonghong He, An amplitude modulation fluorometric method for phytoplankton classified measure, Optik, 125: 2661-2664, 2014.

11. Chan Du, Le Liu, Jun Guo, Yonghong He*, Jihua Guo, Shuqing Sun, Hui Ma, A biosensor using coupled plasmon waveguide resonance combined with hyperspectral fluorescence analysis, JIOHS, 7(1):1450017-1(2014).

12. Chang Huan(常歡) and Sun Shu-Qing(孫樹清)*，Silicon nanoparticles: Preparation, properties, and applications，Chin. Phys. B Vol. 23, No. 8 (2014) 088102

13. Yong Fan, Yu Ding, Yafei Zhang, Hui Ma, Yonghong He and Shuqing Sun*，A SiO2-coated nanoporous alumina membrane for stable label-free waveguide biosensing，RSC Adv., 2014, 4, 62987–62995

14. Xiaocui Wang,ab Guohua Li,ab Yu Dingab and Shuqing Sun*，Understanding the photothermal effect of gold nanostars and nanorods for biomedical applications，RSC Adv., 2014, 4, 30375

15. Jintao Chang, Nan Zeng, Honghui He, Yihong Guo, and Hui Ma, “Removing the polarization artifacts in mueller matrix images recorded with a birefringent gradient-index lens,” J. Biomed. Opt. 19(9), 095001 (2014).

16. Yong Fan, Kazuhiro Hotta, Akira Yamaguchi, Yu Ding, Yonghong He, Norio Teramae, Shuqing Sun, and Hui Ma, "Highly sensitive real-time detection of DNA hybridization by using nanoporous waveguide fluorescence pectroscopy," APPLIED PHYSICS LETTERS 105, 031103 (2014).

17. Yihong Guo, Celong Liu, Nan Zeng, Honghui He, E Du, Yonghong He, and Hui Ma*. “Study on retardance due to well-ordered birefringent cylinders in anisotropic scattering media”, Journal of Biomedical Optics, 19(6):065001, 2014.

18. Jintao Chang, Nan Zeng, Honghui He, Yonghong He, and Hui Ma*. “Single-shot spatially modulated Stokes polarimeter based on a GRIN lens”, Optics Letters, 39(9):2656-2659, 2014.

19. Minghao Sun, Honghui He, Nan Zeng, E Du, Yihong Guo, Cheng Peng, Yonghong He, and Hui Ma*. “Probing microstructural information of anisotropic scattering media using rotation independent polarization parameters”, Applied Optics, 53(14):2949-2955, 2014.

20. Dongzhi Li, Honghui He, Nan Zeng, Weidong Xie, Ran Liao, Jian Wu, Yonghong He, and Hui Ma*. “Influence of absorption in linear polarization imaging of melanoma tissues”, Journal of Innovative Optical Health Sciences, 7(3):1450009, 2014.

21. E Du, Honghui He, Nan Zeng, Celong Liu, Yihong Guo, Ran Liao, Minghao Sun, Yonghong He, and Hui Ma*. “Characteristic features of Mueller matrix patterns for polarization scattering model of biological tissues”, Journal of Innovative Optical Health Sciences, 7(1):1350028, 2014.

22. Honghui He, Minghao Sun, Nan Zeng, E Du, Yihong Guo, Yonghong He, and Hui Ma*. “Mapping local anisotropy axis for scattering media using backscattering Mueller matrix imaging”, Proceedings of SPIE, 8952:89521B, 2014.

23. E Du, Honghui He, Nan Zeng, Yihong Guo, Minghao Sun, and Hui Ma*. “Mueller polarimetry for the detection of cancers”, Proceedings of SPIE, 8935:89350S, 2014.

24. Yihong Guo, Nan Zeng, Honghui He, Celong Liu, E Du, Yonghong He, and Hui Ma*. “Mueller matrix decomposition study on anisotropic medium including cylindrical scatterers and birefringent effect”, Proceedings of SPIE, 8952:89521C, 2014.

2013

1. Heng Shi, Zhiyi Liu, Xiaoxiao Wang, Jun Guo, Le Liu, Lin Luo, Jihua Guo, Hui Ma, Shuqing Sun and Yonghong He. "A symmetrical optical waveguide based surface plasmon resonance biosensing system.", Sensors and Actuators B: Chemical,2013,Vol.185,91-96

2. Honghui He, Nan Zeng, E. Du, Yihong Guo, Dongzhi Li, Ran Liao, Yonghong He and Hui Ma. "Two-dimensional and surface backscattering Mueller matrices of anisotropic sphere-cylinder scattering media: a quantitative study of influence from fibrous scatterers.", Journal of biomedical optics,2013,18(4):046002-046002

3. Honghui He, Nan Zeng, E Du, Yihong Guo, Dongzhi Li, Ran Liao and Hui Ma. "A possible quantitative Mueller matrix transformation technique for anisotropic scattering media."， Photonics and Lasers in Medicine,2013,2(2): 129-137

4. Dongzhi Li, Honghui He, Nan Zeng, E Du, Ran Liao, Yonghong He, Hui Ma, Shaoxiong Liu and Minghua Li. "Polarization imaging and scattering model of cancerous liver tissues.", Journal of Innovative Optical Health Sciences,2013,6(03),1350025

5. Du E, Honghui He, Nan Zeng, Celong Liu, Yihong Guo, Ran Liao, Minghao Sun, Yonghong He and Hui Ma. "Characteristic features of Mueller matrix patterns for polarization scattering model of biological tissues.", Journal of Innovative Optical Health Sciences,2013,6(04),1350028

6. Xinyuan Chong, Le Liu, Zhiyi Liu, Suihua Ma, Jun Guo, Yanhong Ji and Yonghong He. "Detect the Hybridization of Single-Stranded DNA by Parallel Scan Spectral Surface Plasmon Resonance Imaging.", Plasmonics,2013,8(2):1185-1191

7. Yihong Guo, Nan Zeng, Honghui He, Tianliang Yun, E Du, Ran Liao, Yonghong He, and Hui Ma. "A study on forward scattering Mueller matrix decomposition in anisotropic medium.", Optics express,2013,21(15):18361-18370

8. Rui Zhang, Yingbo Liu, Shuqing Sun, "Facile synthesis of water-soluble ZnS quantum dots with strong luminescent emission and biocompatibility", Applied Surface Science, Volume 282, 1 October 2013, Pages 960–964

9. Kexin Zhang, Yaxin Yu, Shuqing Sun, "Facile synthesis l-cysteine capped CdS:Eu quantum dots and their Hg 2+ sensitive properties", Applied Surface Science, Volume 276, 1 July 2013, Pages 333–339

10. Rui Zhang, Yingbo Liu, Libo Yu, Zhen Li and Shuqing Sun, "Preparation of High-quality Biocompatible Carbon dots by Extraction, with new Thoughts on the Luminescence Mechanisms", Nanotechnology, 2013, 24, 225601, doi:10.1088/0957-4484/24/22/225601

11. Yaxin Yu, Kexin Zhang, Shuqing Sun, "Effect of ligands on the photoluminescence properties of water-soluble PbS quantum dots", Journal of Molecular Structure, Volume 1031, 16 January 2013, Pages 194–200

12. Feng Li, Jing Wang, Yuming Lai, Chong Wu, Shuqing Sun, Yonghong He, Hui Ma, "Ultrasensitive and selective detection of copper (II) and mercury (II) ions by dye-coded silver nanoparticle-based SERS probes", Biosensors and Bioelectronics, Volume 39, Issue 1, 15 January 2013, Pages 82–87

13. Yuming Lai, Feng Li, Shuqing Sun, "Controlled surface enhanced resonance Raman scattering (SERRS) in biological environment", Integrated Ferroelectrics: An International Journal, Volume 146, Issue 1, 2013

14. Xuemingyue Han, Shuqing Sun and Tao He. "Preparation and photolithography of self-assembled monolayers of 10-mercaptodecanylphosphonic acid on glass mediated by zirconium for protein patterning.", Colloids and Surfaces B: Biointerfaces,2013,Vol.108,66-71

15. Le Liu, Jingyu Xi, Zenghua Wu, Wenguang Zhang, Haipeng Zhou, Weibin Li and Yonghong He. "Online Spectroscopic Study on the Positive and the Negative Electrolytes in Vanadium Redox Flow Batteries.", Journal of Spectroscopy,2013,vol.2013,Article ID:453980

16. Fei Peng, Jing Wang, Guanglu Ge, Tao He, Lixin Cao, Yonghong He, Hui Ma and Shuqing Sun. "Photochemical reduction of CO2 catalyzed by silicon nanocrystals produced by high energy ball milling.", Materials Letters,2013,Vol.92,65-67

17. Jianghua Li, Ziwei Tu, Zhiyuan Shen, Yunfei Xia, Yonghong He, Songhao Liu and Changshui Chen. "Quantitative measurement of optical attenuation coefficients of cell lines CNE1, CNE2, and NP69 using optical coherence tomography.", Lasers in medical science,2013,28(2),621-625

18. Yuming Lai, Feng Li and Shuqing Sun. "Controlled Surface Enhanced Resonance Raman Scattering (SERRS) in Biological Environment.", Integrated Ferroelectrics,2013,146(1):88-98

19. Hua Qu, Yuming Lai, Dongzi Niu and Shuqing Sun. "Surface-enhanced Raman scattering from magneto-metal nanoparticle assemblies.", Analytica Chimica Acta,2013,763(6),38-42

20. Liu Zhiyi, Peng Qing, Shi Heng,等, MgF2-Au-MgF2-polydopamine based surface plasmon resonance sensor and its application in biomedical systems, ANALYTICAL METHODS, 2013, 5(22), 6306-631

2012

1. Honghui He, Nan Zeng, Tianliang Yun, Yonghong He, Hui Ma. "Linear polarization reflectance of anisotropic scattering medium", Optik -International Journal for Light and Electron Optics,2012,124(17),2619–2622

2. Honghui He, Nan Zeng, Dongzhi Li, Ran Liao, Hui Ma. "Quantitative Mueller matrix polarimetry techniques for biological tissues.", Journal of Innovative Optical Health Sciences,2012,5(03):1250017

3. Sunan Deng, Le Liu, Zhiyi Liu, Zhiyuan Shen, Guohua Li, and Yonghong He. "Line-scanning Raman imaging spectroscopy for detection of fingerprints.", Applied Optics,2012,51(17):3701-3706

4. Zhiyi Liu, Le Liu, Xiaoxiao Wang, Heng Shi, Xinyuan Chong, Suihua Ma, Yanhong Ji, Jihua Guo, Hui Ma and Yonghong He. "Polarization-interferometry-based wavelength-interrogation surface plasmon resonance imager for analysis of microarrays.", Journal of Biomedical Optics,2012,17(3),036002

5. E Du, Honghui He, Nan Zeng, Yihong Guo, Ran Liao, Yonghong He and Hui Ma. "Two-dimensional backscattering Mueller matrix of sphere–cylinder birefringence media.", Journal of biomedical optics,2012,17(12):126016-126016

6. Le Liu, Xiangliang Chen, Zhiyi Liu, Suihua Ma, Chan Du, Yonghong He and Jihua Guo. "Polarization interference interrogation of angular surface plasmon resonance sensors with wide metal film thickness tolerance.", Sensors and Actuators B: Chemical,2012,Vol.173,218-224

7. Yong Fan, Kazuhiro Hotta, Akira Yamaguchi, and Norio Teramae. "Enhanced fluorescence in a nanoporous waveguide and its quantitative analysis.", Optics Express,2012,20(12):12850-12859

8. 陳相亮，劉樂，劉智毅，石恒，馬綏華，何永紅，郭繼華. SPR sensor by method of electro-optic phase modulation and polarization interferometry. 中國光學快報: 英文版，2012，10（B06）：185-187

9. Rui Zhang, Yingbo Liu, Shuqing Sun, "Synthesis and characterization of high-quality colloidal Mn2+-doped ZnS nanoparticles", Optical Materials, 2012,34(11):1788 -1794

10. Jing Wang, Yuexian Liu, Fei Peng, Chunying Chen, Yonghong He, Hui Ma, Lixin Cao, Shuqing Sun, "A General Route to Efficient Functionalization of Silicon Quantum Dots for High-performance Fluorescent Probes", Small, Volume 8, Issue 15, pages 2430–2435, August 6, 2012

11. Kexin Zhang, Yaxin Yu, Shuqing Sun, "Influence of Eu doping on the microstructure and photoluminescence of CdS nanocrystals", Applied Surface Science, Volume 258, Issue 19, 15 July 2012, Pages 7658–7663

12. Yaxin Yu, Kexin Zhang, Shuqing Sun, "One-pot aqueous synthesis of near infrared emitting PbS quantum dots", Applied Surface Science,Volume 258, Issue 18, 1 July 2012, Pages 7181–7187

13. Chong Wu1, Yongsheng Wang, Xuemingyue Han, Xinming Hu, Qianyi Cheng, Baohang Han, Qian Liu, Tianling Ren, Yonghong He, Shuqing Sun and Hui Ma, "Site-selective assembly of quantum dots on patterned self-assembled monolayers fabricated by laser direct-writing", Nanotechnology 23 235302 doi:10.1088/0957-4484/23/23/235302

14. Xuemingyue Han, Chong Wu, Shuqing Sun, "Photochemical reactions of thiol-terminated self-assembled monolayers (SAMs) for micropatterning of gold nanoparticles and controlled surface functionality", Applied Surface Science, Volume 258, Issue 12, 1 April 2012, Pages 5153–5156

15. Chong Wua, Qianyi Cheng, Shuqing Sun, Baohang Han, "Templated patterning of graphene oxide using self-assembled monolayers", Carbon,Volume 50, Issue 3, March 2012, Pages 1083–1089

16. Yaxin Yu, Kexin Zhang, Zhen Li, Shuqing Sun, "Synthesis and luminescence characteristics of DHLA-capped PbSe quantum dots with biocompatibility", Optical Materials,Volume 34, Issue 5, March 2012, Pages 793–798

17. XingYao Wang, Jia Zhou, Cui Miao, YanMing Wang, HuanFeng Wang, Cong Ma, ShuQing Sun, "Synthesis and size control of ferric oxide nanoparticles via a hydrothermal stripping route", Journal of Nanoparticle Research, March 2012, 14:783

18. Cui Yi, Wang Tao, Zhou Ding,等, Growth of Silver Film on Graphene Oxide Pattern, JOURNAL OF PHYSICAL CHEMISTRY C , 2012, 116(33), 17698-17704

2011

1. Ran Liao, Nan Zeng, Dongzhi Li, Tianliang Yun, Yonghong He, and Hui Ma. "Penetration depth of linear polarization imaging for two-layer anisotropic samples.", Applied Optics,2011,50(23):4681-4687

2. Yong Zhou,Nan Zeng,Yanhong Ji,Yao Li,Xiangsong Dai,Peng Li,Lian Duan,Hui Ma and Yonghong He. "Iris as a reflector for differential absorption low-coherence interferometry to measure glucose level in the anterior chamber", Journal of Biomedical Optics,2011,Vol.16(1),015004

3. Yong Zhou, Ye Hu, Nan Zeng, Yanhong Ji, Xiangsong Dai, Peng Li, Hui Ma, and Yonghong He. "Noninvasive monitoring of Pirenoxine Sodium concentration in aqueous humor based on dual-wavelength iris imaging technique.", Biomedical optics express,2011,2(2):231

4. Le Liu, Suihua Ma, Yanhong Ji, Xinyuan Chong, Zhiyi Liu, Yonghong He and Jihua Guo. "A two-dimensional polarization interferometry based parallel scan angular surface plasmon resonance biosensor.", Review of Scientific Instruments,2011,82(2):023109-023109-8

5. Zhiyi Liu, Heng Shi, Le Liu, Sunan Deng, Yanhong Ji, Suihua Ma, Hui Ma and Yonghong He. "Line-Monitoring, Hyperspectral Fluorescence Setup for Simultaneous Multi-Analyte Biosensing.", Sensors,2011,11(11): 10038-10047

6. Zhiyi Liu, Lei Yang, Le Liu, Xinyuan Chong, Jun Guo, Suihua Ma, Yanhong Ji and Yonghong He. "Parallel-scan based microarray imager capable of simultaneous surface plasmon resonance and hyperspectral fluorescence imaging.", Biosensors and Bioelectronics,2011,30(1),180-187

7. Bolin Hu, Nan Zeng, Zhiyi Liu, Yanhong Ji, Weidong Xie, Qing Peng, Yong Zhou, Yonghong He and Hui Ma. "Two-dimensional singlet oxygen imaging with its near-infrared luminescence during photosensitization.", Journal of Biomedical Optics,2011,16(1), 016003-016003-7

8. Zhiyuan Shen, Min Wang, Yanhong Ji, Yonghong He, Xiangsong Dai, Peng Li, and Hui Ma. "Transverse flow velocity quantification using optical coherence tomography with correlation.", Laser physics letters,2011,8(4):318-323

9. Shuqing Sun, David G. Thompson, Duncan Graham and Graham J. Leggett. "DNA nanofabrication by scanning near-field photolithography of oligo (ethylene glycol) terminated SAMs: Controlled scan-rate dependent switching between head group oxidation and tail group degradation.", Journal of Materials Chemistry,2011,21(37): 14173-14177

10. Wang Jing, Sun Shuqing, Peng Fei,等, Efficient one-pot synthesis of highly photoluminescent alkyl-functionalised silicon nanocrystals, CHEMICAL COMMUNICATIONS, 2011, 47(17), 4941-4943

11. Yang Huaichao, Chen Minjiang, Zhou Haiqing,等, Preferential and Reversible Fluorination of Monolayer Graphene, JOURNAL OF PHYSICAL CHEMISTRY C, 2011, 115(34), 16844-16848

12. 李冬至, 廖然, 云天梁, 何永紅, 馬輝. 癌變組織偏振光散射成像. 中國激光, 2011,38(s1):s104002

13. 劉樂, 劉智毅, 陳相亮, 馬綏華, 杜嬋, 何永紅, 郭繼華. 對膜厚不敏感的光譜表面等離子體共振傳感器. 中國激光,2011,38(s1),114004

14. 陽利鋒,曾楠,陳東勝. 偏振敏感光學相干層析對雞肉組織兩種變質過程的表征. 中國激光,2011,38(12),96-101

2010

1. Ran Liao, Xiaoyu Jiang, Yonghong He, Hui Ma, Dongzhi Li, Nan Zeng and Tianliang Yun. "Rotating linear polarization imaging technique for anisotropic tissues.", Journal of biomedical optics,2010,15(3):036014-036014-6

2. Ran Liao, Nan Zeng, Dongzhi Li, Tianliang Yun, Yonghong He and Hui Ma. "A study on penetration depth of polarization imaging.", Journal of Innovative Optical Health Sciences,2010,3(03):177-181

3. Honghui He, Nan Zeng, Wei Li, Tianliang Yun, Ran Liao, Yonghong He and Hui Ma. "Two-dimensional backscattering Mueller matrix of sphere-cylinder scattering medium.", Optics letters,2010,35(14):2323-2325

4. Honghui He, Nan Zeng, Ran Liao, Tianliang Yun, Wei Li, Yonghong He, and Hui Ma. "Application of sphere-cylinder scattering model to skeletal muscle.", Optics express, 2010,18(14):15104-15112

5. Le Liu, Zhaoxu Hu, Suihua Ma, Ying Zhang, Yonghong He and Jihua Guo. "Detection of methane by a surface plasmon resonance sensor based on polarization interferometry and angle modulation.", Optics and Lasers in Engineering,2010,48(12),1182-1185

6. Zhiyi Liu, Suihua Ma, Yanhong Ji, Le Liu, Zhaoxu Hu, Jihua Guo, Hui Ma and Yonghong He. "Quasi-confocal, multichannel parallel scan hyperspectral fluorescence imaging method optimized for analysis of multicolor microarrays.", Analytical chemistry,2010,82(18):7752-7757

7. Zhiyi Liu, Yonghong He, Le Liu, Suihua Ma, Xinyuan Chong, Zhaoxu Hu, Hui Ma and Jihua Guo. "Two-channel, quasi-confocal parallel scan fluorescence imaging for detection of biochips.", Optics and Lasers in Engineering,2010,48(9),849-855

8. 楊彬，劉樂，劉智毅，馬綏華，種心原，何永紅. 線掃描準共焦熒光成像. 光學精密工程，2010，18（5）：1028-1034

9. 劉樂，何永紅，馬綏華，魯衛平，趙欣，張雅歐，郭繼華. 一種新型光譜表面等離子體共振二維探測方法在 DNA 微陣列中的應用. 光譜學與光譜分析, 2010,30(1)，154-158

10. 蔡守東,何永紅,李暉,李志芳,李鵬,代祥松,吳蕾. 眼前節光學相干層析系統的設計及實驗研究. 光電子.激光,2010,21(4),628-631

11. Li Xiaoqing, Yuan Jianjun, Liu Huan,等, Microgel-silica hybrid particles: Strategies for tunable nanostructure, composition, surface property and porphyrin functionalization, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2010, 348(2), 408-415

12. Wong Lu Shin, Janusz Stefan J., Sun Shuqing, Nanoscale Biomolecular Structures on Self-Assembled Monolayers Generated from Modular Pegylated Disulfides, CHEMISTRY-A EUROPEAN JOURNAL, 2010, 16(40), 12234-12243

13. Sun Shuqing, Thompson David, Schmidt Ute, Micro-/nano-patterning of DNA and rapid readout with SERS tags, CHEMICAL COMMUNICATIONS, 2010, 46(29), 5292-5294

14. Barlow Iain, Sun Shuqing, Leggett, Graham J., Synthesis, Monolayer Formation, Characterization, and Nanometer-Scale Photolithographic Patterning of Conjugated Oligomers Bearing Terminal Thioacetates, LANGMUIR, 2010, 26(6), 4449-4458

2009

1. Tianliang Yun, Wei Li, Xiaoyu Jiang and Hui Ma. "Monte Carlo simulation of polarized light scattering in tissues."， Journal of Innovative Optical Health Sciences,2009,2(02):131-135

2. Tianliang Yun, Nan Zeng, Wei Li, Dongzhi Li, Xiaoyu Jiang, and Hui Ma. "Monte Carlo simulation of polarized photon scattering in anisotropic media.", Optics express,2009,17(19):16590-16602

3. Zeng Nan, Jiang Xiaoyu, Gao Qiang, He Yonghong, and Ma Hui. "Linear polarization difference imaging and its potential applications.", Applied optics,2009,48(35):6734-6739

4. 段煉，何永紅，朱銳，馬輝，郭繼華. 三維譜域光學相干層析成像系統的研制. 中國激光，2009，36(10):2528-2533

5. 高強，曾楠，馬輝. 旋轉線偏振光成像方法在紡織品纖維檢測中的應用. 中國激光,2009,36(9):2380-2385

6. 李偉，曾楠，云天梁，馬輝. 各向異性散射介質對偏振光傳播的影響. 中國激光, 2009,36(s1):222

7. 云天梁，曾楠，李偉，馬輝. 各向異性生物組織中偏振光傳輸的模擬與實驗. 光學學報,2009,29(7):1926-1929

2008

1. 張瑩，曾楠，馬綏華，馬輝，何永紅，劉樂，郭繼華. 偏振干涉角度調制 SPR 傳感技術研究及應用進展. 生物技術通報，2008,(S1):481-485

2. 代祥松，曾楠，何永紅，馬輝. 頻域偏振敏感光學相干層析系統的研制及應用研究. 光電子•激光，2008，19(11):1502-1506

3. 何衛紅，何永紅，李鵬，朱毅，邵永紅，梁瑞生，曾楠，馬輝. 眼底 OCT 成像系統的研制. 光學精密工程,2008,16(3):438-443

4. 曾楠，何永紅，馬輝. 用于玉石結構分析的光學相干層析技術. 光學精密工程,2008,16(7):1335

5. 李偉,何永紅,馬輝. 偏振門用于對散射介質成像的蒙特卡羅模擬研究. 光子學報,2008,37(3),518-522

6. 朱銳,何永紅,郭繼華,曾楠,馬輝. 頻域光學相干層析系統的快速色散補償算法研究. 光子學報,2008，37(Sup 2)

7. Nan Zeng, Yonghong He and Hui Ma. "Application of optical coherence tomography in nacre identification and characterization.", Microwave and optical technology letters,2008,50(2):442-445

8. Le Liu, Yonghong He, Ying Zhang, Suihua Ma, Hui Ma, and Jihua Guo. "Parallel scan spectral surface plasmon resonance imaging.", Applied optics,2008,47(30):5616-5621

2007

1. 孫惠霞,李鵬,何永紅,馬輝. 采用OCT系統對組織光學通透的研究. 激光生物學報,2007,16(5):521-526

2. 蔣嘯宇，曾楠，何永紅，馬輝. 基于旋轉偏振角的線偏振掃描成像方法研究. 生物化學與生物物理進展，2007，34（6），659-663

3. 曾楠，何永紅，馬輝，王淑霞. 應用于珍珠檢測的光學相干層析技術. 中國激光， 2007，34(8):1140-1145

4. 朱毅，何永紅，李鵬，高應俊，邵永紅，馬輝. 一種無信息丟失的光學相干層析圖像校正方法. 激光與紅外,2007,37(3):288-291

5. 朱毅，何永紅，李鵬，何衛紅，高應俊，曾楠，馬輝. 光學相干層析圖像層狀結構的增強與定量測量. 光學學報，2007，27(3): 515-520

6. 邵永紅，何永紅，馬輝，南楠，錢龍生，王淑霞. 共振拉曼光譜在體測量類胡蘿卜素含量. 光譜學與光譜分析，2007，27(11):2258-2261

7. 邵永紅,何永紅,馬輝,王淑震,朱毅. 基于醫用顯微鏡的光學相干層析系統設計. 激光雜志,2007,2,017

8. 王淑霞，何永紅，曾楠，高應俊，邵永紅，馬輝. 光學相干層析用于牙齒病變的檢測. 激光生物學報,2007,16(3):355-358

9. 李偉,云天梁,何宏輝,曾楠馬輝. 偏振光在散射介質中的傳播與成像. 中國科學:G輯,2007,37(B10):94-100

10. Wei Li, Yi Wang, Hanrong Shao, Yonghong He, Hui Ma. "Probing rotation dynamics of biomolecules using polarization based fluorescence microscopy.", Microscopy research and technique,2007,70(4):390-395

11. Ducker Robert E., Janusz Stefan, Sun Shuqing, One-step photochemical introduction of nanopatterned protein-binding functionalities to oligo(ethylene glycol)-terminated self-assembled monolayers, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129(48), 14842-+

12. Sun Shuqing, Leggett Graham J., Micrometer and nanometer scale photopatterning of self-assembled monolayers of phosphonic acids on aluminum oxide, NANO LETTERS, 2007, 7(12), 3753-3758

13. Iqbal Parvez, Sun Shuqing, Hanwell Marcus D., Photochemical fabrication of three-dimensional micro- and nano-structured surfaces from a C-60 monoadduct, JOURNAL OF MATERIALS CHEMISTRY , 2008, 18(17), 2016-2021

2006

1. 邵永紅，何永紅，馬輝，王淑霞. 檢測工程聚合物材料新方法研究. 激光與紅外，2006，36(9):878-885

2. 邵永紅，何永紅，馬輝，王淑霞. 鼠眼睛前段光學相干層析成像[J]. 激光與紅外, 2006, 36(8):694-695

3. 邵永紅,何永紅,馬輝,王淑霞,張雅歐. 光學相干層析成像技術用于裸鼠皮膚霉菌感染研究. 激光生物學報,2006,15(5),536-539

4. 邵永紅,何永紅,王淑霞,馬輝. 群相可控光學延遲線色散特性分析. 光學精密工程,2006,14(6)

5. Fanbo Meng and Hui Ma. "A comparison between photon counting histogram and fluorescence intensity distribution analysis.", The Journal of Physical Chemistry B,2006,110(51):25716-25720

6. Fanbo Meng and Hui Ma. "Extended photon counting histogram and fluorescence intensity distribution analysis approaches for optically biased photon counting statistics.", The Journal of Physical Chemistry B,2006,110(19):9667-9673

7. Hanrong Shao, Yonghong He, Wei Li, and Hui Ma. "Polarization-degree imaging contrast in turbid media: a quantitative study.", Applied optics,2006,45(18):4491-4496

8. Zhanliang Sun, Yonghong He, and Jihua Guo. "Surface plasmon resonance sensor based on polarization interferometry and angle modulation.", Applied optics,2006,45(13):3071-3076

9. Sun SQ, Montague M, Critchley K, Fabrication of biological nanostructures by scanning near-field photolithography of chloromethylphenylsiloxane monolayers, NANO LETTERS, 2006, 6(1), 29-33

10. Sun SQ, Mendes P, Critchley K, Fabrication of gold micro- and nanostructures by photolithographic exposure of thiol-stabilized gold nanoparticles, NANO LETTERS, 2006, 6(3), 345-350

2006年以前的

1. 汪雪峰,王毅,蔣艷,馬輝. 雙光子激發熒光各向異性度的成像. 生物化學與生物物理進展,2005,32(2),161-167

2. 孟凡波,陳波,劉廣,丁建英,馬輝. 熒光漲落譜的Monte Carlo模擬與應用. 中國科學:G輯,2005,35(1),62-70

3. 丁建英,陳波,孟凡波,馬輝. 飽和激發情況下的熒光關聯譜測量. 物理學報,2005,53(8),2503-2508

4. Fanbo Meng, Bo Chen, Guang Liu, Jianying Ding and Hui Ma. "Fluorescence fluctuation spectroscopy and its artifacts: simulations and tests.", Science in China Series G: Physics, Mechanics and Astronomy,2005,48(3):336-344

5. Fanbo Meng and Hui Ma. "Fluorescence correlation spectroscopy analysis of diffusion in a laser gradient field: A numerical approach.", The Journal of Physical Chemistry B,2005,109(12):5580-5585

6. Yi Wang, Xue-Feng Wang, Chen Wang and Hui Ma. "Simultaneously multi‐parameter determination of hematonosis cell apoptosis by two‐photon and confocal laser scanning microscopy.", Journal of clinical laboratory analysis,2004,18(5):271-275

7. Sun SQ, Wu PJ, Zhu DB, Electronic switching properties in nanometer-sized Cu-(TCNQ)(2) powder compactions , SOLID STATE COMMUNICATIONS , 1996, 99(4), 237-240

8. Sun SQ, Wu PJ, Zhu DB, Synthesis and electrical properties of some carbonium-metal-(DMIT)(2) complexes, CHINESE CHEMICAL LETTERS , 1996, 7(11), 1054-1056

9. Sun SQ, Zhang B, Wu PJ, Crystal structure of bis(tetraethylammonium) bis[4,5-disulfanyl-1,3-dithiol-2-onato(2-)]nickelate(II) and spectroscopic and electrical properties of related oxidized complexes, JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1997, 2, 277-281

10. Sun SQ, Zhang B, Wu PJ, Crystal structure of bis(tetraethylammonium) bis[4,5-disulfanyl-1,3-dithiol-2-onato(2-)]nickelate(II) and spectroscopic and electrical properties of related oxidized complexes (vol 8, pg 277, 1997), JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1997, 8, 1455-1455

11. Sun SQ, Wu PJ, Zhu DB, The preparation, characterization of amorphous Cu-TCNQ film with a low degree of charge-transfer (DCT) and its electric switching properties, THIN SOLID FILMS, 1997, 301(1-2), 192-196

12. Sun SQ, Wu PJ, Zhu DB, Preparation, crystal structure and electrical conductivity of [EDA] [Ni(dmit)(2)](3) (dmit equals 1,3-dithiole-2-thione-4,5-dithiolate), SYNTHETIC METALS , 1997, 88(3), 243-247

13. Sun SQ, Xu XY, Zhang QC, Synthesis and electrical conductivity of MDA[Ni(dmit)(2)](2), CHINESE CHEMICAL LETTERS , 1997, 8(10), 917-918

14. 孫樹清，吳培基，朱道本，科學通報，1998，43（12），1337

15. Sun SQ, Wu PJ, Zhu DB, Synthesis, electrical properties of [Ni(dmit)(2)](-) complexes and X-ray crystal structure of [EDA][Ni(dmit)(2)] (dmit equals 1,3-dithiol-2-thione-4,5-dithiolate), INORGANICA CHIMICA ACTA, 1998, 268(1), 103-107

16. Sun SQ, Wu PJ, Zhang QC, The new semiconducting magnetic charge transfer salt (BEDT-TTF)(4)center dot H2O center dot Fe(C2O4)(3)center dot C6H5NO2: crystal structure and physical properties, SYNTHETIC METALS , 1998, 94(2), 161-166

17. Sun SQ, Chong KSL, Leggett GJ, Photopatterning of self-assembled. monolayers at 244 nm and applications to the fabrication of functional microstructures and nanostructures, NANOTECHNOLOGY, 2005, 16(9), 1798-1808

18. Chong KSL, Sun SQ, Leggett GJ, Measurement of the kinetics of photo-oxidation of self-assembled monolayers using friction force microscopy, LANGMUIR, 2005, 21(9), 3903-3909

19. Sun S, Leggett GJ, Matching the resolution of electron beam lithography by scanning near-field photolithography, NANO LETTERS, 2004, 4(8), 1381-1384

20. Leggett GJ, Chong KSL, Sun SQ, Scanning near-field photolithography: A new tool for fabricating molecular nanostructures, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2004, 227, U875-U875

21. Sun SQ, Leggett GJ, Generation of nanostructures by scanning near-field photolithography of self-assembled monolayers and wet chemical etching, NANO LETTERS , 2002, 2(11), 1223-1227

22. Sun SQ, Chong KSL, Leggett GJ, Nanoscale molecular patterns fabricated by using scanning near-field optical lithography , JOURNAL OF THE AMERICAN CHEMICAL SOCIETY , 2002, 124(11), 2414-2415

23. Chen P, Sun SQ, Hu YF,等, Structure and solvent effect on the photostability of indolenine cyanine dyes, DYES AND PIGMENTS, 1999, 41(3), 227-231

24. Sun S, Chen P, Zhou S,等, Optical and thermal properties of a cyanine dye medium for next-generation DVD-Rs, IMAGING SCIENCE JOURNAL, 1999, 47(2), 113-117

25. Sun SQ, Wu PJ, Zhu DB, Synthesis and crystal structure of [EDA][Ni(dmit)(2)](3), CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 1999, 18(2), 79-83

26. Sun Shuqing, Chen Ping, Zheng Deshui,等, Optical and thermal properties of some indolenine cyanine dyes used as optical recording materials, Proceedings of the SPIE - The International Society for Optical Engineering, 1998, 3562, 11-16

27. Zhang QC, Wu PJ, Sun SQ, New bisdithiolene metal complex of the 2-thioxo-1,3-dithiole-4,5-dithiolato(dmit) ligand. Preparation, structure and physical properties, SYNTHETIC METALS, 1998, 98(2), 103-106

28. Sun SQ, Wu PJ, Zhu DB, Synthesis, structure and electrical properties of charge transfer complex [MDA] [Pd(dmit)(2)](2), SYNTHETIC METALS , 1998, 96(3), 199-204

29. Sun SQ, Zhang QC, Wu PJ, Synthesis, structure and physical properties of a new charge transfer complex (BEDT-TTF)(4)center dot H2O center dot Fe(C2O3)(3)center dot C6H5NO2, CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 1998, 19(5), 799-801

30. Sun SQ, Xu XY, Wu PJ, Characterization and electrical switching properties of Cu-tetracyanoquinodimethane films formed under different conditions, JOURNAL OF MATERIALS SCIENCE LETTERS, 1998, 17(9), 719-721

馬輝：多個角度看世界

近年來，3D電影越來越受到人們的追捧。走進3D電影院，帶上一副偏振眼鏡，立體影像便展現在眼前。

其實，3D電影只是偏振應用的冰山一角。很少有人意識到，我們周邊實際上是一個偏振光的世界。通過對偏振光性質的測量，我們可以檢測區分不同的癌變組織，可以分辨不同粒徑和成分的氣體污染顆粒物，可以對海洋中的微生物進行現場計數與細致分類……而這些都是清華大學深圳研究生院教授馬輝正在研究的內容。

光學方法是使用時間最長、基礎積淀最深厚、應用范圍最廣泛，并且仍然迅速發展的觀測手段。“照圣經的說法，上帝創造世界做的第一件事就是創造光。”馬輝告訴記者，人類最早就是通過眼睛和光認識周邊世界，隨后用望遠鏡認識星空宇宙，用顯微鏡認識微觀世界，光學測量方法的發展伴隨著自然科學發展的整個歷程。

如今，光學仍然是一個非常具有活力的科學領域，并不斷獲得諾貝爾獎。例如，2008年的綠色熒光蛋白（GFP）、2009年的光纖和CCD以及去年的LED和超分辨成像。“如果你把這些成果串起來，你會發現在這短短幾年中，光學成像方法全鏈條各個環節都獲得了諾貝爾獎：GFP對樣品實現分子特異性對比度增強，LED是新型光源，光纖代表一種新型光路器件，CCD是新型探測器，而超分辨成像則是新的光學成像機理。”可以看出，古老的光學觀測方法正不斷煥發出新的生命力！2013年，聯合國確定2015年為“光之年”。

偏振是光的一個屬性，但很不幸，人類以及絕大多數動物的眼睛對光的偏振并不敏感。因此，盡管偏振這個詞大家都耳熟能詳，但偏振方法的潛力一直沒有得到真正重視，做偏振研究的人很少，偏振的應用也很少。從2004年開始，馬輝將偏振光散射這個看起來并不時髦的領域作為自己的研究方向。

十幾年來，人們在越來越多的領域開始意識到偏振測量的潛力，馬輝滿懷自信地說：“偏振可以大大增加光學方法獲取信息的能力，它將是光學發展的新方向，在信息技術突飛猛進的今天，偏振方法前景無限！”。

實現癌癥早期檢測

馬輝告訴記者，光學方法很適合于生物樣品。它基本不產生損傷，分辨率可以達到亞細胞層次，還可用于從活細胞到組織、器官和個體等不同層次的生物樣品。“但生物組織是不透明的，因為它有散射，當激光照射進人體，光能透進去，但看不清里面的血管和骨頭。散射破壞了光的有序性質，這是光學方法用于生物組織最大的問題。”馬輝解釋道，“利用偏振方法，可以抑制多次散射退偏光子對測量結果的貢獻，提高生物組織淺表層測量的分辨率。”

馬輝最開始研究偏振方法的一個基本目的就是降低散射的影響，提高成像質量。“人們發現，85%以上的癌變首先在上皮組織中產生，提高表皮組織成像的分辨率有可能幫助醫生發現早期癌變。”

偏振測量的另一個功能是獲得生物組織微觀結構的信息。馬輝告訴記者，散射可以改變光的方向，破壞成像結果，但散射也可以影響光的偏振，帶來新的信息。通過研究散射光偏振的變化與散射體的大小、密度、形狀和結構之間的關系，人們可以獲得樣品豐富的微觀結構信息，由此發現生物組織的異常和病變，實現病理診斷。

此外，偏振可以幫助提高淺表層組織成像的分辨率，還能夠測量生物組織微觀結構的變化，在癌癥早期診斷方面具有很好的應用前景。馬輝介紹，他們正與深圳南山醫院病理科合作測量癌變組織。“全偏振成像叫穆勒矩陣成像，我們從醫院找來很多不同類型的癌變樣品做穆勒矩陣成像，包括皮膚基底細胞癌、甲狀腺乳頭狀腺癌、乳腺癌以及宮頸癌等等。現在我們已經有一些證據，能證明全偏振成像的確有可能用于癌變的定量表征，但是我們還需要繼續搜集大量的樣本積累數據。”

2015年，馬輝獲得了國家重大科研儀器研制項目，他將利用這幾年的最新基礎研究成果和技術進展研發模塊化穆勒矩陣顯微鏡，演示其典型臨床應用。同時，他還將建立實驗室研究平臺，針對各個模塊開展原理和方法學探索和工程開發，研究信息提取方法和大數據分析方法，不斷改進儀器，推動產業化。

“2014年，超分辨成像的其中一個諾貝爾獎獲得者赫爾，首先在激光成像中實現了超分辨，但他采用的方法很復雜，不好使用。但赫爾很機靈，他讓萊卡公司把他的方法做成了儀器，給生物學家用。盡管這個儀器現在仍然要賣一千萬人民幣，并且仍然不那么好用，但由于生物學家展示了他的巨大應用價值，白茲格利用貝爾納的工作成果實現了另一種更好用、更便宜的光學超分辨成像方法，最后三個人一起得獎。”馬輝總結道，“光有好概念、好方法還不行，必須推廣出去，讓企業介入把方法變成產品，供更多的人使用。我這個儀器項目就是要發展一系列方法和裝置，并且拉上企業做儀器，為生物學家和醫生提供新的工具，提出新的需求，帶動偏振方法的研究。”

作為探索者，馬輝一路走來碰壁不少，他說：“走很多彎路之后最后發現碰對了，也是一種享受。我覺得做科研就要經歷這些過程！我會沿著這條路繼續往下走，把偏振的潛力不斷挖掘出來。”

偏振開啟一扇門

馬輝做偏振成像和應用是半路出家，他1988年在英國帝國理工學院獲得博士學位，1989年回國，后來加入清華物理系工作，有十幾年時間他一直從事原子分子光譜基礎研究。1995年對馬輝來說是一個轉折點。這一年，他在美國麻省理工學院訪問，與世界頂級科學家合作，研究雙原子分子高激發態光譜。

這一年中，馬輝參觀了很多實驗室。“我在麻省理工學院了解到利用拉曼光譜發現癌變和利用光學相干斷層成像測眼底的工作，在麻省綜合醫院參觀了交叉學科的威爾曼實驗室，在阿貢國家實驗室參觀了高分子光電轉換材料研究組，這些都給了我非常深刻的印象。”這些交叉學科前沿研究讓基礎研究出身的馬輝思索起來，“那一年我確實開始有些想法，覺得自己還是喜歡做偏應用一些的研究”。

回國后馬輝逐步把工作重點轉向生物物理實驗方法研究。從1998年到2003年，他率先在國內開展雙光子熒光成像和光學二次諧波成像，與國際上基本同步。他還建立了熒光漲落譜分析方法，并在熒光偏振成像方面開始探索，“我覺得那時候還真是進展很快，每天都有新的東西”。

2003年，馬輝被調到剛剛建立的清華大學深圳研究生院。深圳是中國改革開放的窗口，有突出的創新文化和快速成長的高技術產業，但高等教育卻滯后于經濟發展。“深圳有著一個很強、很完善的產業鏈結構，而且非常重視應用。在深圳做事，不得不考慮創新將來可能用在哪，能產生多大的影響。”脫離于北京裝備精良的實驗室，馬輝重新思索科研方向。“深圳研究生院有兩個特點，一個是產業合作，一個是學科交叉。既然來到深圳，就必須充分利用這些特點。”

2004年，從英國回來的一位老師加入了馬輝課題組。“他曾做過OCT方面的研究，于是我們決定做OCT產業化。為了同OCT的研究互相呼應，我也開始進行偏振光散射及其應用研究，這是一個全新的研究方向！”

馬輝向記者介紹，OCT就是光學相干斷層掃描儀的簡稱，它可以通過背向散射對眼底視網膜或眼角膜進行微米量級高分辨成像，為醫生提臨床診斷信息。課題組與當地公司合作，開啟了OCT產業化之路。

時至今日，當初合作的小公司已經占據中國眼科OCT產品30%以上市場份額，實驗室畢業的幾個碩士也成為了公司的骨干。與此同時，針對偏振光散射的研究也日益深入，從最初一個應用小課題，逐步產生新問題，帶出新模型、計算程序、實驗方法和應用，形成了完整的研究方向。回想整個發展歷程，馬輝十分感慨：“當初做偏振成像的時候我并沒有很高的期待值，周圍朋友也不認為它有多大的前途，但深入做下去就闖出一條路，而且可能是一條康莊大道。我們周圍是一個偏振光的世界，當你能感受偏振的時候，你會發現這個世界如此豐富多彩！”

最近，偏振研究越來越引起人們的關注，馬輝帶領團隊堅持了10余年，已經形成自己的研究特色，在國際上嶄露頭角。目前馬輝在偏振上專注于做四件事，“第一是測量，我們發展了一系列方法，能夠測得更加準確和迅速；第二是信息提取，就是針對不同應用尋找一些具有特異性的偏振指標，比如某種癌變的臨床診斷指標；第三是信息解釋，就是要知道不同微觀結構如何影響散射光偏振態變化，為解決逆問題提供支撐；第四就是應用，千方百計把偏振用于解決各種實際問題。應用也是我認為最重要的一件事”。

做一個牽線人

對馬輝來說，偏振能為我們提供一個信息寶藏。他打了一個形象的比喻，“不考慮偏振的時候，我們相當于用一個字母來給不同人命名，也就是只能用強度編碼。甲叫a，乙叫aa，丙叫aaa……而偏振能讓我們用單詞命名，jia、yi、bing……穆勒矩陣的16個陣元相當于給了我們16個字母，可以形成各種組合，我們描繪周邊世界的能力一下子提高很多”。另外，偏振方法具有普適性，現有光學方法都可能通過偏振調制升級為偏振方法，應用于不同類型的問題和樣品。

2013年，“霧霾”成為年度關鍵詞，世界上污染最嚴重的10個城市，有7個在中國。為此，我國在霧霾高發的16個省份選擇了43個監測點，以期掌握不同地區PM2.5污染特征及成分差異。“中國的污染很復雜，往往不知道污染源是什么，我們正在同一家公司和環保部門合作，發展一種利用偏振散射對空氣中顆粒物進行計數、分類和源解析的儀器”，他進一步解釋，“這就像一個農貿市場，原先我們只能估算人流總量，現在能告訴你不同時刻男人、女人、小孩各有多少，便于優化管理。”

幾年前，馬輝參與了國家海底觀測試驗網項目，負責數據管理系統。專業敏感性使馬輝開始思考如何將偏振應用到海洋，“通過這個項目我知道了很多海洋方面的需求，我們可以利用偏振方法升級現有的光學技術，提高通過測量所能獲得的信息量”。

從上世紀80、90年代開始，全球平均氣溫比100年前上升了0.48℃，科學家們針對全球變暖這一自然現象提出了種種猜測。馬輝告訴記者，“其實藻類對環境變化影響很大，通過監測海洋里不同類型的藻類，將不同海域里不同藻類的濃度等測出來，科學家就能探究氣候變暖的原因”。

馬輝常將自己的工作比喻為“造槍”，“我們就是要提供新型手段，幫助別人獲得信息。我就像一個造槍的，我不打仗，但我幫助打仗的人，提升軍隊的戰斗力”。

從事科學研究，興趣莫過于最好的助推劑。“我覺得發現問題之后解決問題很好玩，我就是喜歡做科研。”雖然時常奔波于全國各地甚至國外，但馬輝說：“這些年為科研而奔波，我還是挺享受的。”

在馬輝眼中，偏振好似一顆正在發芽的種子。數年來，在他的悉心呵護下，這顆種子破土而出，漸漸長大。他相信偏振在未來的應用潛力終將被更多人認知，就像彩色電視替代了黑白電視，偏振下的新景色將給人類帶來一個翻天覆地的變化。

來源：科學中國人 2016年第3期

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